Baylor Scott & White Heart and Vascular Institute, Baylor University Medical Center, Baylor Scott & White Health, Dallas, Texas, USA.
Baylor Scott & White Heart and Vascular Institute, Baylor University Medical Center, Baylor Scott & White Health, Dallas, Texas, USA; Department of Pathology, Baylor University Medical Center, Baylor Scott & White Health, Dallas, Texas, USA; Department of Internal Medicine (Division of Cardiology), Baylor University Medical Center, Baylor Scott & White Health, Dallas, Texas, USA.
Cardiovasc Pathol. 2020 Sep-Oct;48:107219. doi: 10.1016/j.carpath.2020.107219. Epub 2020 Mar 7.
In this review, we summarize previously reported case reports (n=66) in which the presence of ochronotic pigment was found in one or more cardiovascular structures either at necropsy or after operative excision of a cardiac valve or portions of arteries or both. As illustration, we describe black pigment in operatively excised aortic valves and aorta in 2 patients, both probably examples of secondary ochronosis. Ochronosis appears to have fascinated a number of prominent historical figures in medicine, and this review also summarizes their important contributions to this topic.
在这篇综述中，我们总结了此前报道的 66 例病例报告，这些报告中在尸检或心脏瓣膜或动脉的一部分或全部切除后，在一个或多个心血管结构中发现褐黄病色素。作为例证，我们描述了 2 例患者手术切除的主动脉瓣和主动脉中的黑色色素，这两个病例可能都是继发褐黄病的例子。褐黄病似乎引起了许多医学史上杰出人物的兴趣，本综述还总结了他们在这一主题上的重要贡献。
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