Ahmed Okba F, Kakamad Fahmi H, Salih Abdulwahid M, Mustafa Mohammed Q, Mohammed Shvan H
Mosul Cardiac Center, Mousl, Iraq.
Kscien Organization, Hamdi Str, Azadi Mall, Sulaimani, Kurdistan, Iraq; Smart Health Tower, Madam Mitterrand Str. 46001, Sulaimani, Kurdistan, Iraq; College of Medicine, Department of Surgery, University of Sulaimani, Sulaimani, Kurdistan, Iraq.
Int J Surg Case Rep. 2020;71:196-198. doi: 10.1016/j.ijscr.2020.05.006. Epub 2020 May 22.
Idiopathic deep venous thrombosis is a relatively common clinical finding. The aim of this article is to report and discuss a case of lymphoma presented as DVT in line with SCARE guidelines with brief literature review.
A 19-year-old male presented with right lower limb swelling for two week duration. Examination showed pitting leg edema with warm tense calf. Hematological investigations showed lymphopaenia. Duplex ultrasound showed DVT of right common femoral vein with inguinal lymphadenopathy. Computed tomography showed inguinal lymphadenopahthy. Histopathological examination of lymph node specimen confirmed the diagnosis of Non-Hodgkin's Lymphoma (Burkett's type).
Several series have documented a significantly higher risk of malignancy in patients with presumed idiopathic DVT. Among such patients, 7.6% have been noted to have a malignancy during follow-up; the incidence of occult malignancy diagnosed within 6-12 months of an idiopathic DVT is 2.2-5.3 times higher than that expected from general population estimates.
Idiopathic DVT regardless of age should be approached seriously with a special consideration to malignancy, lymphoma could present only with DVT.
特发性深静脉血栓形成是一种相对常见的临床发现。本文旨在根据SCARE指南报告并讨论一例以深静脉血栓形成为表现的淋巴瘤病例,并进行简要文献回顾。
一名19岁男性因右下肢肿胀两周就诊。检查发现腿部有凹陷性水肿,小腿温暖且紧张。血液学检查显示淋巴细胞减少。双功超声显示右股总静脉深静脉血栓形成伴腹股沟淋巴结病。计算机断层扫描显示腹股沟淋巴结病。淋巴结标本的组织病理学检查确诊为非霍奇金淋巴瘤(伯基特型)。
多项研究记录了疑似特发性深静脉血栓形成患者发生恶性肿瘤的风险显著更高。在这些患者中,7.6%在随访期间被发现患有恶性肿瘤;在特发性深静脉血栓形成后6至12个月内诊断出的隐匿性恶性肿瘤发生率比根据一般人群估计预期的发生率高2.2至5.3倍。
无论年龄大小,特发性深静脉血栓形成都应引起重视,尤其要考虑到恶性肿瘤的可能性,淋巴瘤可能仅表现为深静脉血栓形成。