Cardiovascular Diagnosis and Endoluminal Interventions Unit, Rovigo General Hospital, Rovigo, Italy.
Cardiovascular Diagnosis and Endoluminal Interventions Unit, Rovigo General Hospital, Rovigo, Italy; University of Ferrara, School of Medicine, Ferrara, Italy.
Cardiovasc Revasc Med. 2020 Dec;21(12):1533-1538. doi: 10.1016/j.carrev.2020.05.028. Epub 2020 May 22.
Proximal optimization technique (POT) is a key step during left main (LM) bifurcation stenting. However, after crossover stenting, the ideal position of POT balloon is unclear. We sought to evaluate the biomechanical impact of different POT balloon positions during LM cross-over stenting procedure.
We reconstructed the patient-specific LM bifurcation anatomy, using coronary computed tomography angiography data of 5 consecutive patients (3 males, mean age 66.3 ± 21.6 years) with complex LM bifurcation disease, defined as Medina 1,1,1, evaluated between 1st January 2018 to 1st June 2018 at our center. Finite element analyses were carried out to virtually perform the stenting procedure. POT was virtually performed in a mid (marker just at the carina cut plane), proximal (distal marker 1 mm before the carina) and distal (distal marker 1 mm after the carina) position in each investigated case. Final left circumflex obstruction (SBO%), strut malapposition, elliptical ratio and stent malapposition were evaluated.
The use of both proximal and distal POT resulted in a smaller LM diameter compared to the mid POT. SBO was significantly higher in both proximal and distal configurations compared to mid POT: 38.3 ± 5.1 and 29.3 ± 3.1 versus 18.3 ± 3.6%, respectively. Similarly stent malapposition was higher in both proximal and distal configurations compared to mid POT: 1.3 ± 0.4 and 0.82 ± 1.8 versus 0.78 ± 1.2, respectively.
Mid POT offers the best results in terms of LCx opening maintaining slightly smaller but still acceptable LM and LAD diameters compared to alternative POT configuration.
近端优化技术(POT)是左主干(LM)分叉支架置入术的关键步骤。然而,在交叉支架置入后,POT 球囊的理想位置尚不清楚。我们旨在评估 LM 交叉支架置入术中不同 POT 球囊位置的生物力学影响。
我们使用 5 名连续患者(3 名男性,平均年龄 66.3±21.6 岁)的冠状动脉 CT 血管造影数据,重建了特定于患者的 LM 分叉解剖结构,这些患者患有复杂的 LM 分叉病变,定义为 Medina 1,1,1,于 2018 年 1 月 1 日至 2018 年 6 月 1 日在我们中心进行评估。进行有限元分析以虚拟执行支架置入术。在每个研究病例中,在中间(标记物刚好在嵴切面处)、近端(标记物在嵴前 1mm 处)和远端(标记物在嵴后 1mm 处)位置虚拟进行 POT。评估最终左回旋支阻塞(SBO%)、支架贴壁不良、椭圆率和支架贴壁不良。
与中 POT 相比,近端和远端 POT 的使用导致 LM 直径减小。近端和远端 POT 配置下的 SBO 明显高于中 POT:分别为 38.3±5.1%和 29.3±3.1%与 18.3±3.6%。同样,近端和远端 POT 配置下的支架贴壁不良均高于中 POT:分别为 1.3±0.4%和 0.82±1.8%与 0.78±1.2%。
在 LCx 开口方面,中 POT 提供了最佳的结果,与替代 POT 配置相比,LM 和 LAD 直径略小但仍可接受。