严重急性呼吸综合征冠状病毒2：病毒脱落与传染性的困境。
SARS-CoV-2: The viral shedding vs infectivity dilemma.
作者信息
Widders Arabella, Broom Alex, Broom Jennifer
机构信息
Department of Medicine, Sunshine Coast Hospital and Health Service, Birtinya, 4575, Queensland, Australia.
School of Social and Political Sciences, The University of Sydney, Sydney, 2006, New South Wales, Australia.
出版信息
Infect Dis Health. 2020 Aug;25(3):210-215. doi: 10.1016/j.idh.2020.05.002. Epub 2020 May 20.
Abstract
Since December 2019, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has infected over four million people worldwide. There are multiple reports of prolonged viral shedding in people infected with SARS-CoV-2 but the presence of viral RNA on a test does not necessarily correlate with infectivity. The duration of quarantine required after clinical recovery to definitively prevent transmission is therefore uncertain. In addition, asymptomatic and presymptomatic transmission may occur, and infectivity may be highest early after onset of symptoms, meaning that contact tracing, isolation of exposed individuals and social distancing are essential public health measures to prevent further spread. This review aimed to summarise the evidence around viral shedding vs infectivity of SARS-CoV-2.
摘要
自2019年12月以来，严重急性呼吸综合征冠状病毒2（SARS-CoV-2）已在全球感染了超过400万人。有多项报告指出，感染SARS-CoV-2的人存在病毒长期脱落的情况，但检测中病毒RNA的存在并不一定与传染性相关。因此，临床康复后确定预防传播所需的隔离时间尚不确定。此外，可能会发生无症状和症状出现前的传播，且传染性可能在症状出现后的早期最高，这意味着接触者追踪、对暴露个体的隔离以及社交距离措施是防止进一步传播的重要公共卫生措施。本综述旨在总结关于SARS-CoV-2病毒脱落与传染性的相关证据。
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