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美国结核性腹膜炎住院患者情况:2002 年至 2014 年全国住院患者样本数据库结果。

Hospitalizations for tuberculous peritonitis in the United States: Results from the national inpatient sample database from 2002 to 2014.

机构信息

Department of Internal Medicine, Adolescent and Internal Medicine, Western Michigan University Homer Stryker M D School of Medicine, Kalamazoo, MI, USA.

Department of Biostatistics, Adolescent and Internal Medicine, Western Michigan University Homer Stryker M D School of Medicine, Kalamazoo, MI, USA.

出版信息

Int J Mycobacteriol. 2020 Apr-Jun;9(2):167-172. doi: 10.4103/ijmy.ijmy_68_20.

DOI:10.4103/ijmy.ijmy_68_20
PMID:32474538
Abstract

BACKGROUND

Tuberculosis (TB) is an uncommon disease in the Western hemisphere that can present with peritoneal involvement, as tuberculous peritonitis(TBP) causing abdominal pain and fever. The healthcare and economic burden of TBP in the United States remains unknown.

METHODS

The National Inpatient Sample database was utilized to investigate TBP hospitalizations from 2002 to 2014. Economic expenditures, patient and hospital demographics, and associations of certain comorbidities with TBP were analyzed.

RESULTS

A total of 5878 hospitalizations for TBP occurred over the 12-year duration, with $420 million in-hospital charges. The median patient age was 45 years (interquartile range: 31.1-61.7), with the majority being Hispanic (27.15%). Hospitalizations occurred primarily in the Western (31.3%) and Southern (31.7%) United States. Patient comorbidities and the respective odds ratio associated with TBP included HIV (33.56), continuous peritoneal dialysis (10.49), malnutrition (7.38), liver cirrhosis (6.87), and liver cirrhosis sequelae (6.91). Nearly 6.37% of TBP hospitalizations also had active pulmonary TB.

CONCLUSION

Although TBP is uncommon in the United States, it should be considered in patients presenting with abdominal pain and fever and a history of HIV, continuous peritoneal dialysis, malnutrition, liver cirrhosis, or liver cirrhosis sequelae.

摘要

背景

结核病(TB)在西半球是一种罕见疾病,但可能会出现腹膜受累,表现为结核性腹膜炎(TBP),引起腹痛和发热。在美国,TBP 的医疗保健和经济负担尚不清楚。

方法

利用国家住院患者样本数据库调查了 2002 年至 2014 年 TBP 的住院情况。分析了经济支出、患者和医院人口统计学特征,以及某些合并症与 TBP 的关联。

结果

在 12 年的时间里,共有 5878 例 TBP 住院治疗,住院费用为 4.2 亿美元。患者的中位年龄为 45 岁(四分位距:31.1-61.7),大多数为西班牙裔(27.15%)。住院治疗主要发生在美国西部(31.3%)和南部(31.7%)。患者合并症与 TBP 相关的比值比包括 HIV(33.56%)、持续腹膜透析(10.49%)、营养不良(7.38%)、肝硬化(6.87%)和肝硬化后遗症(6.91%)。近 6.37%的 TBP 住院患者还伴有活动性肺结核。

结论

尽管 TBP 在 美国并不常见,但对于出现腹痛和发热、HIV、持续腹膜透析、营养不良、肝硬化或肝硬化后遗症病史的患者,应考虑 TBP。

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