Department of Surgery, College of Medicine, King Saud University, Riyadh, Kingdom of Saudi Arabia.
Department of Pathology, College of Medicine, King Saud University, Riyadh, Kingdom of Saudi Arabia.
Int J Mycobacteriol. 2020 Apr-Jun;9(2):205-208. doi: 10.4103/ijmy.ijmy_28_20.
The purpose of this study was to assess the risk of venous thromboembolism (VTE) and the potential need for thromboprophylaxis in patients with tuberculosis (TB).
A total of 103 patients who underwent treatment for TB at the King Khalid University Hospital in Riyadh between February 2015 to May 2018, the percentage of patients diagnosed with TB who developed VTE was assessed. This was a retrospective cohort study conducted at King Khalid University Hospital in Riyadh. Fisher's exact test was used to analyze the categorical variables.P < 0.05 was considered statistically significant.
Our data showed the prevalence of VTE in TB patients to be 2.93% (3/103). VTE occurred irrespective of the type of TB (pulmonary and/or extrapulmonary). All TB patients with VTE showed no significant association with factors such as human immunodeficiency virus coinfection, malignancy, and multidrug-resistant TB.
Our study showed that TB patients in Saudi Arabia may be at a higher risk for developing VTE and should be carefully monitored as potential candidates for additional thromboprophylaxis; further studies are recommended to establish more reliable assessment and recommendations.
本研究旨在评估结核病（TB）患者发生静脉血栓栓塞症（VTE）的风险和潜在的血栓预防需求。
我们对 2015 年 2 月至 2018 年 5 月在利雅得的哈立德国王大学医院接受 TB 治疗的 103 例患者进行了回顾性队列研究，评估了诊断为 TB 的患者中发生 VTE 的比例。Fisher 确切检验用于分析分类变量。P<0.05 被认为具有统计学意义。
我们的数据显示，TB 患者中 VTE 的患病率为 2.93%（3/103）。VTE 的发生与 TB 的类型（肺和/或肺外）无关。所有发生 VTE 的 TB 患者与人类免疫缺陷病毒合并感染、恶性肿瘤和耐多药结核等因素均无显著相关性。
我们的研究表明，沙特阿拉伯的 TB 患者可能有更高的发生 VTE 的风险，应作为潜在的额外血栓预防候选者进行密切监测；建议进行进一步的研究以建立更可靠的评估和建议。
