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在携带耐碳青霉烯类肠杆菌科细菌（CRE）的住院患者中，后续发生的与CRE相关的感染：抗生素使用及其他因素的影响

Subsequent carbapenem-resistant Enterobacteriaceae (CRE)-associated infections among hospitalized patients with CRE colonization: Impact of antibiotic use and other factors.

作者信息

Khawcharoenporn Thana, Laichuthai Wipada

机构信息

Division of Infectious Diseases, Thammasat University, Pathumthani, Thailand.

Department of Internal Medicine, Thammasat University, Pathumthani, Thailand.

出版信息

Infect Control Hosp Epidemiol. 2020 Sep;41(9):1084-1089. doi: 10.1017/ice.2020.220. Epub 2020 Jun 1.

DOI:10.1017/ice.2020.220
PMID:32475370
Abstract

We demonstrated a 20% rate of subsequent carbapenem-resistant Enterobacteriaceae (CRE)-associated infections among hospitalized CRE carriers. Independent factors associated with the infections were number of colonization sites, central-line insertion, and receiving vancomycin before colonization. These findings underscore the importance of antibiotic stewardship and device-related infection control measures to prevent CRE infections.

摘要

我们证明，在住院的耐碳青霉烯类肠杆菌科细菌（CRE）携带者中，后续发生CRE相关感染的比例为20%。与感染相关的独立因素包括定植部位数量、中心静脉置管以及在定植前接受万古霉素治疗。这些发现强调了抗生素管理和与设备相关的感染控制措施对预防CRE感染的重要性。

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