Department of Neurological Surgery, University of Pittsburgh, Epilepsy Center, 200 Lothrop Street, Suite B400, Pittsburgh, PA, USA.
Cleveland Clinic Lerner College of Medicine, Cleveland, OH, USA.
Neurosurg Clin N Am. 2020 Jul;31(3):387-394. doi: 10.1016/j.nec.2020.03.010.
Resective epilepsy surgery relies on accurate preoperative localization of the epileptogenic zone (EZ), so presurgical evaluation is necessary to obtain the most accurate information from clinical, anatomic, and neurophysiologic aspects, with the ultimate goal of performing an individualized surgical treatment. The noninvasive methods of seizure localization are complementary and results must be interpreted in conjunction, in an attempt to compose localization hypotheses of the anatomic location of the EZ. Stereoelectroencephalography is an extraoperative invasive method that is applied in patients with medically refractory focal epilepsy in order to anatomically define the EZ and the related functional cortical areas.
致痫灶切除术依赖于术前对致痫区（EZ）的精确定位，因此术前评估是必要的，以便从临床、解剖和神经生理学方面获得最准确的信息，最终目标是进行个体化的手术治疗。癫痫定位的非侵入性方法是互补的，结果必须结合起来解释，试图构成 EZ 的解剖位置的定位假设。立体脑电图是一种手术外的侵入性方法，应用于药物难治性局灶性癫痫患者，以明确 EZ 及其相关功能皮质区的解剖定位。
