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一名尼日利亚女性患者表现为非典型大动脉炎

Takayasu's Arteritis Presenting Atypically in a Female Nigerian.

作者信息

Odunlami G J, Okunola O O, Olaosebikan H, Aderibigbe A S, Ajibade A I

机构信息

Rheumatology Unit, Department of Medicine, OAUTHC, Ile-Ife, Nigeria.

Nephrology Unit, Department of Medicine, OAUTHC, Ile-Ife, Nigeria.

出版信息

West Afr J Med. 2020 Jul-Aug;37(3):284-289.

PMID:32476124
Abstract

Takayasu's arteritis (TA) is an idiopathic form of large vessel granulomatous vasculitis that mainly affects the aorta and its major branches, most frequently in young women under 50 years. While traditionally, it is a disease found commonly in Asia continent, it has also been reported from different parts of the world, albeit with a few reports from Sub-Sahara Africa. The clinical presentations are variable and are commonly from systemic inflammation, vascular occlusive diseases and aneurysm. Asymptomatic cases of TA have been documented and are usually discovered incidentally on physical examination. Common vascular symptoms from different series include vascular claudication, reduced or absent pulse, carotid bruit, hypertension and headache. Facial mononeuropathy and retinal ischaemic changes are rare findings in TA. However, occlusive disease of ulnar artery has not been reported in TA despite our extensive literature search. Here, we present a 48-year-old woman, who was admitted via the medical emergency with community acquired pneumonia but was incidentally diagnosed with Takayasu arteritis with lower motor neuron facial nerve palsy, unilateral blindness, and ulnar artery occlusion. Multidisciplinary management was instituted and patient was discharged after resolution of community acquired pneumonia, vascular claudication, and chronic headache. TA often presents asymptomatically and sometimes with atypical features and thus we suggest high index of suspicion and detailed cardio-vascular examination in young individuals with unexplained chronic headache, facial nerve palsy and visual symptoms.

摘要

高安动脉炎(TA)是一种特发性大血管肉芽肿性血管炎,主要累及主动脉及其主要分支,多见于50岁以下的年轻女性。传统上,该病常见于亚洲大陆,但世界各地也均有报道,不过撒哈拉以南非洲地区的报道较少。其临床表现多样,常见于全身炎症、血管闭塞性疾病和动脉瘤。TA的无症状病例已被记录在案,通常在体格检查时偶然发现。不同系列报道的常见血管症状包括血管性跛行、脉搏减弱或消失、颈动脉杂音、高血压和头痛。面部单神经病和视网膜缺血性改变在TA中较为罕见。然而,尽管我们进行了广泛的文献检索,但尚未见TA合并尺动脉闭塞性疾病的报道。在此,我们报告一名48岁女性,因社区获得性肺炎经医疗急诊入院,却偶然诊断为高安动脉炎,伴有下运动神经元性面神经麻痹、单眼失明和尺动脉闭塞。我们采取了多学科管理,患者在社区获得性肺炎、血管性跛行和慢性头痛症状缓解后出院。TA常无症状出现,有时还伴有非典型特征,因此我们建议,对于原因不明的慢性头痛、面神经麻痹和视觉症状的年轻患者,应提高警惕并进行详细的心血管检查。

相似文献

1
Takayasu's Arteritis Presenting Atypically in a Female Nigerian.一名尼日利亚女性患者表现为非典型大动脉炎
West Afr J Med. 2020 Jul-Aug;37(3):284-289.
2
Small vessel involvement in Takayasu's arteritis.小血管受累在 Takayasu 动脉炎。
Autoimmun Rev. 2013 Jan;12(3):355-62. doi: 10.1016/j.autrev.2012.05.010. Epub 2012 Jun 9.
3
Clinical, angiographic profile and percutaneous endovascular management of Takayasu's arteritis - A single centre experience.大动脉炎的临床、血管造影特征及经皮血管腔内治疗——单中心经验
Int J Cardiol. 2016 Oct 1;220:924-8. doi: 10.1016/j.ijcard.2016.06.194. Epub 2016 Jun 26.
4
Takayasu's Arteritis Presenting with Headache and Peripheral Facial Palsy: A Case Report.以头痛和周围性面瘫为表现的高安动脉炎:一例报告
J Tehran Heart Cent. 2016 Oct 3;11(4):195-197.
5
Digital Gangrene is a Rare Presentation of Takayasu's Arteritis.数字坏疽是 Takayasu 动脉炎的一种罕见表现。
Mymensingh Med J. 2023 Oct;32(4):1208-1213.
6
Factors Associated With Need for Revascularisation in Non-coronary Arterial Occlusive Lesions Secondary to Takayasu's Arteritis.高安动脉炎继发非冠状动脉闭塞性病变中与血运重建需求相关的因素。
Eur J Vasc Endovasc Surg. 2017 Sep;54(3):397-404. doi: 10.1016/j.ejvs.2017.05.020. Epub 2017 Jul 11.
7
Delayed diagnosis of Takayasu's arteritis: total abdominal aorta occlusion treated with axillo-bifemoral bypass.高安动脉炎的延迟诊断:经腋-双股动脉旁路移植术治疗的腹主动脉完全闭塞
J Rheumatol. 2004 Feb;31(2):393-5.
8
[Fulminant course of a Takayasu's arteritis and rare mesenteric arterial maninfestion].[高安动脉炎的暴发性病程及罕见的肠系膜动脉受累]
Z Rheumatol. 2006 Oct;65(6):520, 522-6. doi: 10.1007/s00393-005-0023-2.
9
[A 29-year-old man with Takayasu's arteritis].一名患有高安动脉炎的29岁男性。
Vasa. 2006 May;35(2):118-22. doi: 10.1024/0301-1526.35.2.118.
10
Common carotid artery aneurysm revealing Takayasu's arteritis.颈总动脉动脉瘤提示多发性大动脉炎。
J Stroke Cerebrovasc Dis. 2011 Nov;20(6):556-8. doi: 10.1016/j.jstrokecerebrovasdis.2010.03.004. Epub 2010 Aug 17.

引用本文的文献

1
[Takayasu's disease: an underdiagnosed entity in Sub-Saharan Africa. Report of five Gabonese cases].[高安氏病:撒哈拉以南非洲地区一种诊断不足的疾病。五例加蓬病例报告]
Med Trop Sante Int. 2022 Sep 22;2(3). doi: 10.48327/mtsi.v2i3.2022.272. eCollection 2022 Sep 30.