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胶原基质包裹联合骨髓血注射治疗复杂半月板撕裂:至少 5 年随访后的临床疗效和生存率。

Complex Meniscus Tears Treated with Collagen Matrix Wrapping and Bone Marrow Blood Injection: Clinical Effectiveness and Survivorship after a Minimum of 5 Years' Follow-Up.

机构信息

Rehasport Clinic, Poznań, Poland.

En Chambaz, Môtier, Switzerland.

出版信息

Cartilage. 2021 Dec;13(1_suppl):228S-238S. doi: 10.1177/1947603520924762. Epub 2020 Jun 1.

Abstract

. To determine the 5-year success rate of the "all-inside" technique of arthroscopic meniscus suture and collagen membrane wrapping along with bone marrow blood injection, to evaluate the progression of degenerative changes and the impact of simultaneous anteriro cruciate ligament (ACL) reconstruction. . Fifty-four consecutive patients with complex meniscal tears were treated with the previously described technique. The subjective scores (International Knee Documentation Committee 2000, Lysholm, EQ-5D-5L) and Barret clinical criteria of meniscal healing were recorded. Magnetic resonance images (MRIs) were assessed at 2 and 5 years postoperatively, using the Whole-Organ Magnetic Resonance Imaging Score (WORMS) criteria. Kaplan-Meier survival analyses were performed in order to assess the survivorship after the index procedure. Thirty-nine patients were divided into 2 groups: group A-isolated meniscus repair and group B-meniscus repair with concurrent ACL reconstruction. . Fifty-four patients were treated and 44 were available for analysis. There was a statistically significant improvement in subjective scores and clinical assessment between the preoperative, 2-year follow-up, and 5-year follow-up time points. EQ-5D-5L utility value was 0.9 ± 1 at final follow-up. The WORMS osteoarthritis severity grade had increased from 6.9 ± 5.0 points at the 2-year follow-up to 11.1 ± 9.6 points at the 5-year follow-up ( < 0.001). There was a significant difference between the groups after 60 months. The overall survival rate at final follow-up was 88%. . The treatment option evaluated in this study has shown very good mid-term clinical and MRI-based outcomes as well as a favorable survival rate. Simultaneous ACL reconstruction is likely a factor for osteoarthritis progression.

摘要

. 为了确定关节镜半月板缝合和胶原膜包裹联合骨髓血注射的“全内”技术的 5 年成功率,评估退行性变化的进展和同时进行前交叉韧带(ACL)重建的影响。. 对 54 例复杂半月板撕裂患者采用上述技术进行治疗。记录主观评分(国际膝关节文献委员会 2000 年,Lysholm,EQ-5D-5L)和半月板愈合的 Barrett 临床标准。术后 2 年和 5 年分别采用磁共振成像(MRI)评估(WORMS)标准,采用全器官磁共振成像评分(WORMS)标准。为了评估指数手术后的生存情况,进行了 Kaplan-Meier 生存分析。. 54 例患者接受了治疗,44 例患者可进行分析。主观评分和临床评估在术前、2 年随访和 5 年随访时间点之间均有统计学显著改善。最终随访时 EQ-5D-5L 效用值为 0.9±1。WORMS 骨关节炎严重程度等级从 2 年随访时的 6.9±5.0 点增加到 5 年随访时的 11.1±9.6 点(<0.001)。60 个月后两组间有显著差异。最终随访时的总生存率为 88%。. 本研究评估的治疗选择显示出非常好的中期临床和基于 MRI 的结果以及有利的生存率。同时进行 ACL 重建可能是骨关节炎进展的一个因素。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1d8e/8808947/2b31442331bb/10.1177_1947603520924762-fig1.jpg

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