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[主动脉内膜节律性结构在动脉粥样硬化发展中的作用]

[The role of rhythmic structures of the aortic intima in the development of atherosclerosis].

作者信息

Vikhert A M, Zhdanov V S, Osis Iu G

出版信息

Ter Arkh. 1988;60(12):7-12.

PMID:3247658
Abstract

A study was made of 606 specimens from dead males aged 20 to 39. The frequency and area of rhythmical structures (RS) of lipid spots and fibrous patches of aorta were determined after staining of aortae with Sudan IV. RSs were revealed in persons aged 20-29 and 30-39 in 70%. RS in the abdominal aorta was more frequent than in the thoracic aorta: at the age of 20-29-57.4 +/- 3 and 48.6 +/- 3.1%, at the age of 30-39-65.2 +/- 2.6 and 38.5 +/- 2.5%, respectively. There was no correlation between the mean expression of lipidosis and the frequency of RS in the aortic intima. In the presence of aortic RS fibrous patches were 4-5-fold more frequent than in their absence. In young patients fibrous patches often (in 80%) have macroscopic signs of development on RS site. The area of fibrous patches was 4-6-fold larger in persons with aortic RS than in those without RS.

摘要

对606例年龄在20至39岁之间的男性死者标本进行了研究。用苏丹IV对主动脉进行染色后,测定了主动脉脂质斑和纤维斑块的节律性结构(RS)的频率和面积。在20 - 29岁和30 - 39岁的人群中,70%发现有RS。腹主动脉中的RS比胸主动脉更常见:在20 - 29岁时分别为57.4±3%和48.6±3.1%,在30 - 39岁时分别为65.2±2.6%和38.5±2.5%。脂质沉积的平均表达与主动脉内膜RS的频率之间没有相关性。存在主动脉RS时,纤维斑块的出现频率比不存在时高4至5倍。在年轻患者中,纤维斑块常在RS部位(80%)出现宏观发育迹象。有主动脉RS的人的纤维斑块面积比没有RS的人大约4至6倍。

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