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采用激光碎石术成功治疗十二指肠内大的嵌顿性胆囊结石、Bouveret 综合征:一例报告。

Successful endoscopic treatment of a large impacted gallstone in the duodenum using laser lithotripsy, Bouveret's syndrome: A case report.

机构信息

Department of Gastroenterology, Franciscus Gasthuis & Vlietland, Rotterdam 3045 PM, Zuid-Holland, Netherlands.

Department of Surgery, Franciscus Gasthuis & Vlietland, Rotterdam 3045 PM, Zuid-Holland, Netherlands.

出版信息

World J Gastroenterol. 2020 May 21;26(19):2458-2463. doi: 10.3748/wjg.v26.i19.2458.

Abstract

BACKGROUND

Bouveret´s syndrome is defined as a gastric outlet obstruction after passage of a gallstone through a fistula into the duodenum. Due to its rarity, the diagnosis of Bouveret's syndrome is often delayed and causes a high morbidity and mortality rate.

CASE SUMMARY

A 93-year-old female presented with worsening pain in the right upper abdomen and vomiting. A gastroscopy revealed fluid retention caused by a massive obstructive stone in the bulbus. Endoscopic laser lithotripsy of the impacted stone was planned after multidisciplinary consultation. A Dornier Medilas H Solvo lithotripsy 350 µm laser fiber (10 Hz, 2 Joules) was used to disintegrate the stone into smaller pieces. The patient recovered completely.

CONCLUSION

A mechanical obstruction due to a gallstone that has entered the gastrointestinal tract is a complication that appears in 0.3%-0.5% of patients who have cholelithiasis. Stones larger than 2 cm can become impacted in the digestive tract, which occurs mostly in the terminal ileum. In approximately 1%-3% of cases, the stones cause obstruction in the duodenum. This phenomenon is called Bouveret's syndrome. As this condition is mostly observed in elderly individuals with multiple comorbidities, treatment by an open surgical approach is unsuitable. Endoscopic removal is the preferred technique. The benefit of using laser lithotripsy is the precise targeting of energy onto the stone with minimal tissue injury. Endoscopic laser lithotripsy is a safe and feasible treatment option for Bouveret's syndrome.

摘要

背景

Bouveret 综合征定义为胆石通过瘘管进入十二指肠后引起的胃出口梗阻。由于其罕见性,Bouveret 综合征的诊断常常被延误,导致高发病率和死亡率。

病例摘要

一名 93 岁女性因右上腹痛加剧和呕吐就诊。胃镜检查显示球部有巨大阻塞性结石导致的液体潴留。经多学科会诊后计划进行内镜下激光碎石术。使用 Dornier Medilas H Solvo 碎石 350 µm 激光纤维(10 Hz,2 焦耳)将结石粉碎成更小的碎片。患者完全康复。

结论

进入胃肠道的胆石引起的机械性梗阻是胆道结石患者中 0.3%-0.5%出现的并发症。大于 2 cm 的结石可在消化道中嵌顿,主要发生在回肠末端。约 1%-3%的情况下,结石引起十二指肠梗阻。这种现象称为 Bouveret 综合征。由于这种情况主要发生在有多种合并症的老年患者中,开放性手术治疗并不合适。内镜下取石是首选技术。激光碎石术的优点是能量能精确靶向结石,对组织损伤最小。内镜下激光碎石术是治疗 Bouveret 综合征的一种安全可行的治疗选择。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/18be/7243648/9bd64d817c6b/WJG-26-2458-g001.jpg

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