结核病治疗的新尝试：多药耐药结核病（MTB）一例化疗治疗失败后采用自体细胞因子诱导的杀伤细胞治疗
New attempt in tuberculosis treatment: autologous cytokine-induced killer after chemotherapy treatment failure in a case of multi-drug resistant tuberculosis (MTB).
作者信息
Xu Jun-Chi, Chen Xin-Nian, Ye Zhi-Jian, Wu Mei-Ying, Shi Cui-Lin, Tang Pei-Jun, Chen Hui, Zhu Xiao-Yan, Song Hua-Feng, Ping Xu
机构信息
Inspection Center. The Fifth People's Hospital of Suzhou, Suzhou, China.
Key Laboratory of TB Prevention and Cure of Suzhou, Suzhou, China.
出版信息
Sarcoidosis Vasc Diffuse Lung Dis. 2017;34(1):97-99. doi: 10.36141/svdld.v34i1.5084. Epub 2017 Apr 28.
A 32-year-old woman was diagnosed as pulmonary tuberculosis 15 years ago and recurred several times due to long-term nonstandard treatment. Drug sensitivity test indicated that multidrug-resistant tuberculosis had emerged and we determined relevant therapeutic schedule according to this result. However, it didn't show any amelioration of the disease after 3-month chemotherapy. We formulated 3-course CIK immunotherapy based on patient's condition. After 3 courses of immunotherapy, we found obvious amelioration of the patient's condition. And there was no recurrence during the follow-up in the past 3 years. Therefore, we considered that the CIK immunotherapy is an effective method for tuberculosis treatment and recurrence prevention. .
一名32岁女性15年前被诊断为肺结核，因长期不规范治疗多次复发。药敏试验表明已出现耐多药结核病，我们据此结果制定了相关治疗方案。然而，化疗3个月后病情未见任何改善。我们根据患者病情制定了3个疗程的CIK免疫治疗方案。经过3个疗程的免疫治疗，我们发现患者病情明显改善。在过去3年的随访中未出现复发。因此，我们认为CIK免疫治疗是治疗结核病和预防复发的有效方法。
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