显微镜下多血管炎中的弥漫性支气管扩张和气流阻塞。
Diffuse bronchiectasis and airflow obstruction in granulomatosis with polyangiitis.
作者信息
Barba T, Khouatra C, Traclet J J, Cordier J F, Cottin V
机构信息
Hospices Civils de Lyon, Hôpital Edouard Herriot, Service de Médecine Interne, Lyon, France.
Hospices Civils de Lyon, Hôpital Louis Pradel, Centre national de référence des maladies pulmonaires rares, Service de pneumologie, Lyon, France, Univ Lyon, Université Lyon I, INRA, UMR754, Lyon, France.
出版信息
Sarcoidosis Vasc Diffuse Lung Dis. 2018;35(1):81-84. doi: 10.36141/svdld.v35i1.6298. Epub 2018 Apr 28.
Parenchymal lung nodes and diffuse intra-alveolar hemorrhage are the archetypal pulmonary manifestations of Granulomatosis with Polyangiitis (GPA). The occurrence of diffuse bronchiectasis and airflow obstruction during GPA is unusual. We report here 3 patients with GPA who developed diffuse bronchiectasis during follow-up. The airflow obstruction seemed then to evolve independently from the GPA itself and ultimately led to respiratory insufficiency. Bronchiectases promoted the occurrence of opportunistic infections, especially with atypical mycobacteria. .
肺实质结节和弥漫性肺泡出血是肉芽肿性多血管炎（GPA）典型的肺部表现。GPA 期间出现弥漫性支气管扩张和气流阻塞并不常见。我们在此报告 3 例 GPA 患者，他们在随访期间出现了弥漫性支气管扩张。气流阻塞似乎随后独立于 GPA 本身发展，最终导致呼吸功能不全。支气管扩张促进了机会性感染的发生，尤其是非典型分枝杆菌感染。
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