对于患有镰状细胞贫血且尽管存在高胆红素血症但MRI或CT血管造影呈阴性的患者，用于检测“黄变症”的脑脊液分光光度法能否用于检测蛛网膜下腔动脉瘤渗漏？
Can CSF spectrophotometry for "Xanthochromia" be used to detect leaking subarachnoid aneurysms in patients with sickle cell anemia with negative MRI or CT angiogram despite hyperbilirubinemia?
作者信息
Siu Wan Yung, Thomas William, Trivedi Rikin, Hogan Alexandra, Siddiqi Umbareen, Sarker Anita, Besser Martin Wolfgang
机构信息
Department of Haematology Addenbrooke's Hospital Cambridge UK.
Department of Neurosurgery Addenbrooke's Hospital Cambridge UK.
出版信息
Clin Case Rep. 2020 Mar 12;8(5):894-899. doi: 10.1002/ccr3.2775. eCollection 2020 May.
Abstract
CSF (Cerebrospinal Fluid) xanthochromia by spectroscopy should not be dismissed in the context of hyperbilirubinemia in a patient with sickle cell anemia. Xanthochromia detected by spectrophotometry offers a vital clue that further invasive diagnosis is required.
摘要
在镰状细胞贫血患者出现高胆红素血症的情况下，不应忽视通过光谱学检测脑脊液（CSF）黄变症。通过分光光度法检测到的黄变症提供了一个重要线索，表明需要进一步进行侵入性诊断。
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