Ghafoerkhan Rina S, van Heemstra Henriette E, Scholte Willem F, van der Kolk Joriene R J, Ter Heide Jackie June F, de la Rie Simone M, Verhaak Linda M, Snippe Evelien, Boelen Paul A
ARQ National Psychotrauma Centre, Nienoord 5, 1112 XE Diemen, The Netherlands.
2Department of Clinical Psychology, Utrecht University, Heidelberglaan 1, 3584 CS Utrecht, The Netherlands.
Pilot Feasibility Stud. 2020 May 21;6:69. doi: 10.1186/s40814-020-00613-1. eCollection 2020.
Displaced victims of interpersonal violence, such as refugees, asylum seekers, and victims of sexual exploitation, are growing in numbers and are often suffering from a post-traumatic stress disorder (PTSD). At the same time, these victims are known to benefit less from trauma-focused therapy (TFT) and to be less compliant to treatment. The objective of this paper is to describe the rationale and research protocol of an ongoing trial that aims to evaluate different variables that might influence the feasibility of TFT for the study population. Specifically, perceived daily stress, emotion regulation, and mood are investigated as predictors of change in PTSD symptoms during a trauma-focused therapy (narrative exposure therapy (NET)). The feasibility of administering measures tapping these constructs repeatedly during treatment will also be evaluated.
METHODS/DESIGN: Using an observational treatment design, 80 displaced victims of interpersonal violence will be measured before, during, and after partaking in NET. Several questionnaires tapping PTSD plus the aforementioned possible predictors of PTSD change will be administered: Post-traumatic Stress Disorder Checklist-5, Perceived Stress Scale, Difficulties in Emotion Regulation Scale-18 (pre-test, post-test, and follow-up),subscale impulsivity of the Difficulties in Emotion Regulation Scale-18, Perceived Stress Scale short version, Primary Care Post-traumatic Stress Disorder and a single Mood item (each session). Multilevel modelling will be used to examine the relation between the possible predictors and treatment outcome.
The present study is the first to examine the interplay of facilitating and interfering factors possibly impacting treatment feasibility and effectiveness in displaced victims of interpersonal violence with PTSD receiving NET, using repeated measures. The current study can help to improve future treatment based on individual characteristics.
Netherlands Trial Register: NTR7353, retrospectively registered. Date of registration: July 11, 2018.
人际暴力的流离失所受害者，如难民、寻求庇护者和性剥削受害者，数量不断增加，且常常患有创伤后应激障碍（PTSD）。与此同时，已知这些受害者从创伤聚焦疗法（TFT）中获益较少，且对治疗的依从性较低。本文的目的是描述一项正在进行的试验的基本原理和研究方案，该试验旨在评估可能影响研究人群接受TFT可行性的不同变量。具体而言，将调查感知到的日常压力、情绪调节和情绪，作为创伤聚焦疗法（叙事暴露疗法（NET））期间PTSD症状变化的预测因素。还将评估在治疗期间反复采用测量这些结构的方法的可行性。
方法/设计：采用观察性治疗设计，80名人际暴力流离失所受害者将在参加NET之前、期间和之后进行测量。将发放几份用于评估PTSD以及上述PTSD变化可能预测因素的问卷：创伤后应激障碍检查表-5、感知压力量表、情绪调节困难量表-18（预测试、后测试和随访）、情绪调节困难量表-18的冲动性分量表、感知压力量表简版、初级保健创伤后应激障碍和一个单一情绪项目（每次治疗）。将使用多水平模型来检验可能的预测因素与治疗结果之间的关系。
本研究首次使用重复测量方法，研究了可能影响接受NET治疗的人际暴力流离失所PTSD受害者治疗可行性和有效性的促进因素和干扰因素之间的相互作用。本研究有助于根据个体特征改进未来的治疗。
荷兰试验注册库：NTR7353，追溯注册。注册日期：2018年7月11日。
