White S D, Ohman J L
Department of Medicine, School of Veterinary Medicine, Tufts University, North Grafton, MA 01536.
Am J Vet Res. 1988 Nov;49(11):1873-5.
Intradermal skin testing with 4 cat allergens was performed on 40 dogs. The allergens used were a commercial preparation, cat allergen 1, cat pelt extract, and cat serum. Twenty dogs had inhalant allergies (canine atopy) and 20 dogs were healthy. The dogs in these 2 groups were further allotted to groups of dogs with or without exposure to cats. Cat pelt extract was the only allergen that caused a statistically significant (P less than 0.025) difference in the number of positive reactions in healthy vs allergic dogs, with healthy dogs having the greater number of positive reactions. Seven (35%) of the 20 dogs with no known exposure to cats had positive reactions to at least one of the allergens. In dogs that had been exposed to cats, positive reactions developed in twice the number of dogs without clinical signs of canine atopy, compared with those with clinical signs of canine atopy. These data showed that dogs do become sensitized to cat allergen, but that this sensitization may not indicate known exposure to cats or clinical disease.
对40只狗进行了4种猫过敏原的皮内皮肤试验。所用的过敏原是一种商业制剂、猫过敏原1、猫皮提取物和猫血清。20只狗有吸入性过敏（犬异位性皮炎），20只狗健康。这两组狗又被进一步分为接触过猫和未接触过猫的狗群。猫皮提取物是唯一一种在健康狗和过敏狗的阳性反应数量上引起统计学显著差异（P小于0.025）的过敏原，健康狗的阳性反应数量更多。20只未知接触过猫的狗中，有7只（35%）对至少一种过敏原呈阳性反应。在接触过猫的狗中，没有犬异位性皮炎临床症状的狗出现阳性反应的数量是有犬异位性皮炎临床症状的狗的两倍。这些数据表明，狗确实会对猫过敏原致敏，但这种致敏可能并不表明已知接触过猫或患有临床疾病。
