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基于 APP 的认知行为疗法在初级保健中治疗产后抑郁症的效果:一项随机对照试验。

Effectiveness of an app-based cognitive behavioral therapy program for postpartum depression in primary care: A randomized controlled trial.

机构信息

Neuroscience Research Center, Institute of Neuropharmacology, Kerman University of Medical Sciences, Kerman, Iran.

Medical Informatics Research Center, Institute for Futures Studies in Health, Kerman University of Medical Sciences, Kerman, Iran.

出版信息

Int J Med Inform. 2020 Sep;141:104145. doi: 10.1016/j.ijmedinf.2020.104145. Epub 2020 May 24.

Abstract

OBJECTIVE

The objective of this study was to examine the effect of mobile phone applications (App) based cognitive behavioral therapy (CBT) on postpartum depression.

METHOD

A non-blinded parallel-group randomized controlled trial was conducted. The study population consisted of women attended to three health care centers in Kerman, Iran. Participants were recruited between September and November 2018, and randomized 1:1 to either the intervention group (mobile application access) or control group (no mobile application access). All participants completed the Edinburgh Postnatal Depression Scale (EPDS) at the baseline and 2 months after baseline. Data were analyzed using inferential statistics including chi-square, independent sample t-test, paired t-test and linear regression.

RESULTS

A total of 75 women with an average age of 27 years participated in this study. Before the intervention, there was no statistically significant difference between the EPDS score between the two groups (p > 0.001). However, in the intervention group, the average EPDS score after intervention was 8.18 and in the control group was 15.05, which was statistically significant (p < 0.001).

CONCLUSION

These findings provide proof that providing a CBT program using a mobile application can lead to clinically important improvements in outcomes for mothers who suffer from postpartum depression.

摘要

目的

本研究旨在探讨基于手机应用程序(App)的认知行为疗法(CBT)对产后抑郁症的影响。

方法

采用非盲平行组随机对照试验。研究人群为伊朗克尔曼三个医疗中心就诊的女性。参与者于 2018 年 9 月至 11 月招募,并按 1:1 随机分为干预组(可访问移动应用程序)或对照组(无法访问移动应用程序)。所有参与者均在基线和基线后 2 个月完成爱丁堡产后抑郁量表(EPDS)。采用卡方检验、独立样本 t 检验、配对 t 检验和线性回归等推断性统计方法分析数据。

结果

共有 75 名平均年龄为 27 岁的女性参加了这项研究。在干预前,两组的 EPDS 评分无统计学差异(p>0.001)。然而,在干预组中,干预后的平均 EPDS 评分为 8.18,而对照组为 15.05,具有统计学意义(p<0.001)。

结论

这些发现证明,提供使用移动应用程序的 CBT 方案可以显著改善患有产后抑郁症的母亲的结局。

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