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[电离辐射作用下再生肌肉组织与骨骼肌的组织相互作用]

[Tissue interactions of regenerating muscle tissue with skeletal muscle under the effect of ionizing radiation].

作者信息

Popova M F, Buliakova N V, Azarova V S

出版信息

Arkh Anat Gistol Embriol. 1988 Dec;95(12):35-40.

PMID:3248049
Abstract

The effect of the muscle tissue, ground into a fine chyme, to restoration of the m. gastrocnemius ability to posttraumatic regeneration after x-ray radiation in the doses 20--30 Gy, has been studied in 64 non-inbred white male rats with the body mass about 200 g. The ground muscle is a viscous mass, consisting of finest scraps of muscle fibers, pieces of sarcolemmal tubules with 2--3 nuclei and separate cells. The great destruction of the muscle stroma relieves metabolites to get out and to diffuse. As demonstrate the histological investigations carried out for 1 month, an essential part of the muscle autotransplant, put into the irradiated extremity, regenerates up to formation of differentiated muscle fibers and promotes to restore the regenerative activity in the irradiated m. gastrocnemius.

摘要

在64只体重约200克的非近交系雄性白鼠身上,研究了研磨成精细乳糜状的肌肉组织对受20 - 30戈瑞剂量X射线辐射后创伤后腓肠肌再生能力恢复的影响。研磨后的肌肉是一种粘性物质,由肌肉纤维的细微碎片、带有2 - 3个细胞核的肌膜小管碎片和单个细胞组成。肌肉基质的大量破坏使代谢产物得以排出并扩散。为期1个月的组织学研究表明,植入受辐射肢体的肌肉自体移植组织的很大一部分会再生,直至形成分化的肌肉纤维,并有助于恢复受辐射腓肠肌的再生活性。

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