Department of Obstetrics and Gynecology, McGill University, Montréal, QC.
Department of Obstetrics and Gynecology, McGill University, Montréal, QC.
J Obstet Gynaecol Can. 2020 Nov;42(11):1385-1387. doi: 10.1016/j.jogc.2020.02.128. Epub 2020 Mar 24.
Tranexamic acid reduces blood loss in patients with bleeding diatheses and is used in a number of gynaecologic and non-gynaecologic conditions CASE: We discuss the case of a 27-year-old woman with type 1 von Willebrand disease, who presented with a two-year history of severe mittelschmerz secondary to recurrent hemorrhagic cysts. The patient refused oral contraception and reported that traditional analgesia did not significantly alleviate symptoms. We theorized that the underlying von Willebrand disease compounded the degree of hemorrhage into her recurrent cysts. As such, a trial of mid-cycle tranexamic acid was offered, which drastically improved her symptoms.
We report that the use of mid-cycle tranexamic acid in patients with recurrent haemorrhagic cysts can lower ovulation-associated pain.
氨甲环酸可减少出血倾向患者的出血量，并在许多妇科和非妇科疾病中使用。
我们讨论了一名 27 岁患有 1 型血管性血友病的女性患者的病例，她因反复出血性囊肿而出现两年严重的中腹痛。该患者拒绝口服避孕药，并报告传统止痛药不能显著缓解症状。我们推测潜在的血管性血友病加重了她反复囊肿的出血程度。因此，给予她中期周期氨甲环酸治疗，极大地改善了她的症状。
我们报告称，在反复出血性囊肿患者中使用中期周期氨甲环酸可以降低与排卵相关的疼痛。
