J Am Pharm Assoc (2003). 2020 Sep-Oct;60(5):750-756. doi: 10.1016/j.japh.2020.03.008. Epub 2020 May 29.
To create a novel screening tool that identified patients who were most likely to benefit from pharmacist in-home medication reviews.
Single-center, retrospective study.
A total of 25 homebound patients in Forsyth County, NC, aged 60 years or older with physical or cognitive impairments and enrolled in home-based primary care or transitional and supportive care programs participated in the study. Pharmacy resident-provider pairs conducted home visits for all patients in the study. Pharmacy residents assessed the subjective risk (high, medium, low) of medication nonadherence using information obtained from home visits (health literacy, support network, medications, and detection of something unexpected related to medications). An electronic medical record-based risk score was simultaneously calculated using screening tool components (i.e., electronic frailty index score, LACE+ index [length of stay in the hospital, acuity of admission, comorbidity, emergency department utilization in the 6 months before admission], and 2015 American Geriatric Society Beers Criteria).
The electronic medical record-based screening tool numerical risk scores were compared with pharmacy resident subjective risk assessments using tree-based classification models to determine screening tool components that best predicted pharmacy residents' subjective assessment of patients' likelihood of benefit from in-home pharmacist medication review. Following the study, satisfaction surveys were given to providers and pharmacy residents.
The best predictor of high-risk patients was an electronic frailty index score greater than 0.32 (indicating very frail) or LACE+ index greater than or equal to 59 (at high risk for hospital readmission). Pharmacy residents and providers agreed that homebound patients at high-risk for medication noncompliance benefited from pharmacist time and attention in home visits.
In homebound older persons, this screening tool allowed for the identification of patients at high-risk for medication nonadherence through targeted in-home pharmacist medication reviews. Further studies are needed to validate the accuracy of this tool internally and externally.
创建一种新的筛选工具,以确定最有可能从药剂师上门药物审查中受益的患者。
单中心回顾性研究。
北卡罗来纳州福赛斯县的 25 名居家患者参与了这项研究,他们年龄在 60 岁或以上,有身体或认知障碍,并参加了基于家庭的初级保健或过渡和支持性护理计划。药剂师住院医师-提供者对研究中的所有患者进行家访。药剂师住院医师使用家访中获得的信息(健康素养、支持网络、药物以及与药物相关的意外情况检测)评估药物不依从的主观风险(高、中、低)。同时使用筛选工具组件(即电子虚弱指数评分、LACE+ 指数[住院时间、入院时的严重程度、合并症、入院前 6 个月内急诊就诊]和 2015 年美国老年医学会 Beers 标准)计算基于电子病历的风险评分。
基于电子病历的筛选工具数值风险评分与药剂师住院医师的主观风险评估进行比较,使用基于树的分类模型来确定最佳预测药剂师住院医师对患者从上门药剂师药物审查中获益的可能性的筛选工具组件。研究结束后,向提供者和药剂师住院医师发放了满意度调查。
对于居家的老年人,该筛选工具通过有针对性的上门药剂师药物审查,可以识别出药物不依从高风险的患者。需要进一步的研究来验证该工具在内部和外部的准确性。