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增强性传播感染伴侣通知咨询和医务人员协助的伴侣服务对南非开普敦的性传播感染诊断发病率和伴侣转诊的影响:随机对照试验。

Effects of enhanced STI partner notification counselling and provider-assisted partner services on partner referral and the incidence of STI diagnosis in Cape Town, South Africa: randomised controlled trial.

机构信息

Health Systems Research Unit, South African Medical Research Council, Tygerberg, South Africa

School of Public Health and Family Medicine, University of Cape Town, Rondebosch, South Africa.

出版信息

Sex Transm Infect. 2021 Feb;97(1):38-44. doi: 10.1136/sextrans-2020-054499. Epub 2020 Jun 1.

Abstract

OBJECTIVES

We investigated the effects of an enhanced partner notification (PN) counselling intervention with the offer of provider-assisted referral among people diagnosed with STI in a Cape Town public clinic.

METHODS

Participants were adults diagnosed with STI at a community clinic. After the standard STI consultation, participants were randomly allocated in a 1:1:1 ratio to (1) 'HE': 20 min health education; (2) 'RR': 45 min risk reduction skills counselling; or (3) 'ePN': 45 min enhanced partner notification communication skills counselling and the offer of provider-assisted referral. The primary outcome was the incidence of repeat STI diagnoses during the 12 months after recruitment, and the secondary outcome was participants' reports 2 weeks after diagnosis of notifying recent partners. Incidence rate ratios (IRRs) were used to compare the incidence rates between arms using a Poisson regression model.

RESULTS

The sample included 1050 participants, 350 per group, diagnosed with STI between June 2014 and August 2017. We reviewed 1048 (99%) participant records, and identified 136 repeat STI diagnoses in the ePN arm, 138 in the RR arm and 141 in the HE arm. There was no difference in the annual incidence of STI diagnosis between the ePN and HE arms (IRR: 1.0; 95% CI 0.7 to 1.3), or between the RR and HE arms (IRR: 0.9; 95% CI 0.7 to 1.2). There was a greater chance of a partner being notified in the ePN condition compared with the HE condition, 64.3% compared with 53.8%, but no difference between the RR and HE arms.

CONCLUSIONS

PN counselling and education with provider-assisted services has the potential to change the behaviour of people diagnosed with STIs, increasing the number of partners they notify by more than 10%. However, these changes in behaviour did not lead to a reduction of repeat STI diagnoses.

TRIAL REGISTRATION NUMBER

PACTR201606001682364.

摘要

目的

我们调查了在开普敦一家诊所诊断出性传播感染的人群中,强化性伴侣通知(PN)咨询干预措施与提供辅助转介相结合对性伴侣通知的影响。

方法

参与者为在社区诊所诊断出性传播感染的成年人。在进行标准性传播感染咨询后,参与者以 1:1:1 的比例随机分配到以下三组之一:(1)“HE”:20 分钟健康教育;(2)“RR”:45 分钟降低风险技能咨询;或(3)“ePN”:45 分钟强化性伴侣通知沟通技巧咨询和提供辅助转介。主要结局是在招募后 12 个月内重复性传播感染的发生率,次要结局是参与者在诊断后 2 周报告通知最近性伴侣的情况。使用泊松回归模型,采用发病率比值比(IRR)比较各组之间的发生率。

结果

该样本包括 2014 年 6 月至 2017 年 8 月期间诊断出性传播感染的 1050 名参与者,每组 350 名。我们回顾了 1048 名(99%)参与者的记录,在 ePN 组中发现了 136 例重复性传播感染诊断,在 RR 组中发现了 138 例,在 HE 组中发现了 141 例。ePN 组和 HE 组之间性传播感染的年度发病率没有差异(IRR:1.0;95%CI 0.7 至 1.3),RR 组和 HE 组之间也没有差异(IRR:0.9;95%CI 0.7 至 1.2)。与 HE 组相比,ePN 组通知性伴侣的可能性更大,分别为 64.3%和 53.8%,但 RR 组与 HE 组之间没有差异。

结论

PN 咨询和教育与提供辅助服务相结合,有可能改变诊断出性传播感染的人的行为,使他们通知的性伴侣数量增加 10%以上。然而,这些行为的改变并没有导致重复性传播感染的诊断减少。

试验注册编号

PACTR201606001682364。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/baee/7841487/49873abd44d0/sextrans-2020-054499f01.jpg

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