Beaumont G
J Int Med Res. 1977;5(1 Suppl):46-50.
The subject of dosage of clomipramine (Anafranil) in depression and in obsessional and phobic disorders is discussed. The expectation of success is reported and a recommendation made to adopt flexible dosage. Some side-effects are considered and stress is laid on distinguishing between unwanted pharmacological effects and serious toxic effects. Serious adverse reactions are rare. Contra-indications, both relative and absolute, are discussed. The importance of possible drug interactions is emphasized.
本文讨论了氯米帕明（安拿芬尼）在抑郁症、强迫症和恐惧症治疗中的剂量问题。报告了成功的预期情况，并建议采用灵活的剂量。文中考虑了一些副作用，并强调要区分不良药理作用和严重毒性作用。严重不良反应很少见。讨论了相对和绝对的禁忌症。强调了可能的药物相互作用的重要性。
