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上颌窦成釉细胞瘤:经鼻内镜治疗

Maxillary Sinus Ameloblastoma: Transnasal Endoscopic Management.

作者信息

Karp John, Xiong Wei, Derikvand Sara, Javer Amin

机构信息

School of Medicine, Royal College of Surgeons in Ireland, Dublin, Ireland.

Department of Pathology and Laboratory Medicine, University of British Columbia and St Paul's Sinus Centre, Vancouver, British Columbia, Canada.

出版信息

Ear Nose Throat J. 2021 Dec;100(10_suppl):908S-912S. doi: 10.1177/0145561320930555. Epub 2020 Jun 2.

Abstract

Ameloblastoma (AM) is a slow growing and aggressive benign tumor with an odontogenic epithelial origin arising from the mandible or maxilla. The odontogenic neoplasm invades local tissues asymptomatically and accounts for 1% of oral tumors and over 10% of odontogenic tumors. A 64-year-old man with a history of allergic fungal rhinosinusitis (AFRS) undergoing a revision image-guided endoscopic sinus surgery was found to have a fibrous mass suspicious of malignancy projecting inferolaterally and attached to the floor of the left maxillary sinus. Diagnostic biopsies were taken, and additional surgery was required to successfully resect the tumor via a transnasal endoscopic dissection. Multiple permanent pathology samples concluded the diagnosis of an AM. Endoscopic investigations led to the incidental discovery and ultimate complete endoscopic resection of the AM. The utilization of an endoscopic resection compared to the traditional maxillectomy with reconstruction results in significant less short and long-term morbidity for the patient.

摘要

成釉细胞瘤(AM)是一种生长缓慢且具有侵袭性的良性肿瘤,起源于下颌骨或上颌骨的牙源性上皮。这种牙源性肿瘤无症状地侵犯局部组织,占口腔肿瘤的1%,在牙源性肿瘤中占比超过10%。一名有变应性真菌性鼻窦炎(AFRS)病史的64岁男性正在接受修正的影像引导下鼻内镜鼻窦手术,术中发现一个可疑为恶性的纤维性肿物,该肿物向外侧下方突出并附着于左上颌窦底部。进行了诊断性活检,还需要额外的手术通过经鼻内镜切除术成功切除肿瘤。多个永久性病理样本确诊为AM。内镜检查偶然发现了该AM并最终通过内镜完全切除。与传统上颌骨切除术加重建相比,内镜切除术给患者带来的短期和长期发病率显著更低。

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