[Surgical resection of 48 patients with malignant disease of the pancreas and periampullary region].

Fourty-eight patients with malignant disease of pancreas and periampullary region treated by surgery from Jan. 1966 to June 1985 are analyzed. Of these patients, 44 underwent pancreaticoduodenectomy, 2 had resection of the body and tail of pancreas, 1 had total pancreatectomy and 1 had tumor resection only. The operative mortality was 12.5%. The overall 5-year survival rate was 48.2%. The 5- and 10-year survival rates of the 44 patients by pancreaticoduodenectomy were 46.4% and 37.5%, respectively. Experience and technique on the postoperative complications were analyzed. The prevention of massive bleeding during operation were suggested. Apart from the cigarette drain to the pancreaticoduodenal bed, an easy and effective method for draining the digestive juice from the lumen near anastomosis of the pancreaticojejunostomy and choledochojejunostomy is suggested.