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[采用脱蛋白牛骨矿物质进行后期入路上颌窦底提升并分期植入种植体:一项前瞻性临床研究的3年以上随访]

[Later approach sinus floor elevation using deproteinized bovine bone mineral with staged implant placement: follow-up for more than 3 years in a prospective clinical study].

作者信息

Wang J, Liu Y, Guo Z Z, Xie C, Cao Y Z, Yu Z, Lei C, Li D H

机构信息

Department of Implantology, School of Stomatology, The Fourth Military Medical University & State Key Laboratory of Military Stomatology & National Clinical Research Center for Oral Diseases & Shaanxi Engineering Research Center for Dental Materials and Advanced Manufacture, Xi'an 710032, China.

Department of Stomatology, The 81st Group Army Hospital of Chinese PLA, Zhangjiakou 075000, China.

出版信息

Zhonghua Kou Qiang Yi Xue Za Zhi. 2020 Jun 9;55(6):378-382. doi: 10.3760/cma.j.cn112144-20191119-00415.

DOI:10.3760/cma.j.cn112144-20191119-00415
PMID:32486566
Abstract

To evaluate clinical effect of deproteinized bovine bone for delayed implantation after fenestration. This trial is a continuation of a prospective clinical trial. From May 2011 to February 2015 in Department of Implantology, School of Stomatology, The Fourth Military Medical University after planting division of 55 cases of maxillary teeth missing area of residual alveolar bone height ≤5 mm patients. There were 21 female and 34 male patients, their average age were (55.2±7.1) years. A total of 62 side fenestration of maxillary sinus floor lift, clinical and imaging examination, evaluation of implant retention rate, complications, peripheral soft tissue health and marginal bone resorption. A total of 82 implants were followed up in 41 patients. The average follow-up time was (51.8±14.3) months (36-78 months). The follow-up rate of the maxillary sinus was 75.8% (47/62), the follow-up rate of the implant was 73.9% (82/111), and the implant survival rate was 98.8% (81/82). The bone resorption results at the implant margins were (0.64±0.63) mm (-0.28 mm, 1.47 mm) in the near and (0.49±0.73) mm (-0.51 mm, 1.21 mm) in the far, the improved hemorrhage index was 0.46±0.72, the improved plaque index was 0.60±0.87, and the keratinized mucosa width was (2.14±1.22) mm. The incidence rate of peri-implant mucositis was 28.4% (23/81) among 23 implants, and there was no complication of peri-implant inflammation. This study shows that under the condition of insufficient sinus ridge spacing in the maxillary posterior area, it is feasible to use bovine bone alone to remove protein for delayed implantation of maxillary sinus floor elevation by windowing, and the clinical effect is reliable.

摘要

评估脱蛋白牛骨用于开窗术后延期种植的临床效果。本试验是一项前瞻性临床试验的延续。2011年5月至2015年2月,在第四军医大学口腔医学院种植科,对55例上颌牙缺失区剩余牙槽骨高度≤5mm的患者进行种植分区。其中女性21例,男性34例,平均年龄为(55.2±7.1)岁。共对上颌窦底进行62侧开窗提升,进行临床及影像学检查,评估种植体留存率、并发症、周边软组织健康状况及边缘骨吸收情况。41例患者共82枚种植体进行随访,平均随访时间为(51.8±14.3)个月(36 - 78个月)。上颌窦随访率为75.8%(47/62),种植体随访率为73.9%(82/111),种植体存留率为98.8%(81/82)。种植体边缘骨吸收结果近中为(0.64±0.63)mm(-0.28mm,1.47mm),远中为(0.49±0.73)mm(-0.51mm,1.21mm),改良出血指数为0.46±0.72,改良菌斑指数为0.60±0.87,角化黏膜宽度为(2.14±1.22)mm。81枚种植体中有23枚发生种植体周围黏膜炎,发生率为28.4%(23/81),未发生种植体周围炎并发症。本研究表明,在上颌后牙区窦嵴间距不足的情况下,单独使用脱蛋白牛骨进行上颌窦底开窗延期种植是可行的,临床效果可靠。

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