子宫肌瘤子宫动脉栓塞治疗的新进展。
Updates in uterine artery embolization for leiomyomas.
机构信息
Division of Minimally Invasive Gynecologic Surgery, Department of Obstetrics and Gynecology and Women's Health, Albert Einstein College of Medicine/Montefiore Medical Center, Bronx, New York, USA.
出版信息
Curr Opin Obstet Gynecol. 2020 Aug;32(4):269-276. doi: 10.1097/GCO.0000000000000635.
PURPOSE OF REVIEW
Uterine leiomyomas are a common condition estimated to affect 70-80% of reproductive-aged women. An evolving body of evidence continues to guide our understanding of various surgical and interventional treatment options, such as uterine artery embolization (UAE). This article provides an updated review of novel findings regarding UAE.
RECENT FINDINGS
Despite an abundance of observational studies and several small randomized controlled trials, large scale long-term comparative efficacy studies are lacking. Although short-term outcomes continue to be favorable, recent trials show reoperation rate of up to 35% in 10 years and may raise some concerns regarding ovarian reserve, fertility and pregnancy outcomes.
SUMMARY
UAE remains a safe and effective alternative to surgery in the management of leiomyomas. A deeper investigation into understanding this treatment's optimal use in various patient populations is needed.
目的综述
子宫肌瘤是一种常见的疾病，估计有 70-80%的育龄妇女受其影响。越来越多的证据不断加深我们对各种手术和介入治疗选择的理解，例如子宫动脉栓塞术（UAE）。本文对 UAE 的新发现进行了更新综述。
最近的发现
尽管有大量的观察性研究和几项小型随机对照试验，但缺乏大规模的长期比较疗效研究。尽管短期结果仍然是有利的，但最近的试验显示，10 年内的再次手术率高达 35%，这可能会引发对卵巢储备、生育和妊娠结局的一些担忧。
总结
UAE 仍然是一种安全有效的手术替代疗法，可用于治疗子宫肌瘤。需要更深入地研究如何在各种患者群体中优化使用这种治疗方法。
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