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在新冠疫情期间处理急性门静脉高压性胃病出血:是创新之举还是必要之策?

Managing Acute Portal Hypertensive Gastropathy Bleed During the Time of COVID-19 Pandemic: Novelty or Necessity?

作者信息

Philips Cyriac A, Kumbar Sandeep, Ahamed Rizwan, Augustine Philip

机构信息

Gastroenterology, Cochin Gastroenterology Group, Kochi, IND.

Gastroenterology, Ernakulam Medical Center, Kochi, IND.

出版信息

Cureus. 2020 May 28;12(5):e8333. doi: 10.7759/cureus.8333.

DOI:10.7759/cureus.8333
PMID:32489751
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7255538/
Abstract

Acute bleeding from portal hypertensive gastropathy (PHG) is an extremely rare event in the natural history of cirrhosis. The treatment recommendations include portal pressure reduction strategies including pharmacotherapy with vasoactive agents and beta-blockers and interventional strategies such as transjugular intrahepatic portosystemic shunt placement. In this report, we present the case of a patient with cirrhosis in whom acute PHG-related bleed was managed with endoscopic band ligation, a therapeutic modality which has not been described in current literature. Our decision to re-purpose a technique for variceal bleeding stems from the fact that during the ongoing COVID-19 pandemic, the technical assistance, resource availability, and sourcing of materials that were required for us to follow recommended management guidelines for acute PHG-related bleed was severely affected due to imposed lockdown between districts and states.

摘要

门静脉高压性胃病(PHG)引起的急性出血在肝硬化自然病程中极为罕见。治疗建议包括降低门静脉压力的策略,如使用血管活性药物和β受体阻滞剂进行药物治疗,以及经颈静脉肝内门体分流术等介入策略。在本报告中,我们介绍了一例肝硬化患者,其急性PHG相关出血通过内镜下套扎术进行治疗,这是一种目前文献中尚未描述的治疗方式。我们决定将一种用于静脉曲张出血的技术重新用于该病例,原因是在当前的新冠疫情期间,由于地区和州之间实施封锁,我们遵循急性PHG相关出血推荐管理指南所需的技术援助、资源可用性和材料采购受到严重影响。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d51b/7255538/232f980be3a7/cureus-0012-00000008333-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d51b/7255538/232f980be3a7/cureus-0012-00000008333-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d51b/7255538/232f980be3a7/cureus-0012-00000008333-i01.jpg

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Managing Acute Portal Hypertensive Gastropathy Bleed During the Time of COVID-19 Pandemic: Novelty or Necessity?在新冠疫情期间处理急性门静脉高压性胃病出血:是创新之举还是必要之策?
Cureus. 2020 May 28;12(5):e8333. doi: 10.7759/cureus.8333.
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本文引用的文献

1
Efficacy of argon plasma coagulation in the management of portal hypertensive gastropathy.氩离子凝固术治疗门静脉高压性胃病的疗效
Endosc Int Open. 2016 Oct;4(10):E1057-E1062. doi: 10.1055/s-0042-114979. Epub 2016 Oct 6.
2
Changes in portal blood flow and liver functions in cirrhotics during Ramadan fasting in the summer; a pilot study.夏季斋月禁食期间肝硬化患者门静脉血流和肝功能的变化;一项初步研究。
Gastroenterol Hepatol Bed Bench. 2016 Summer;9(3):180-8.
3
Portal hypertensive gastropathy and gastric antral vascular ectasia.门静脉高压性胃病和胃窦血管扩张症
Curr Opin Gastroenterol. 2015 Nov;31(6):506-12. doi: 10.1097/MOG.0000000000000214.
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Management of portal hypertensive gastropathy and other bleeding.门静脉高压性胃病和其他出血的处理。
Clin Mol Hepatol. 2014 Mar;20(1):1-5. doi: 10.3350/cmh.2014.20.1.1. Epub 2014 Mar 26.
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Effect of Ramadan fasting on acute upper gastrointestinal bleeding.斋月禁食对急性上消化道出血的影响。
J Res Med Sci. 2013 Mar;18(3):230-3.