病灶内注射丝裂霉素C治疗复发性尿道狭窄疾病后发生尿道-海绵体瘘

Rehder Peter, Pedrini Marco, Jelisejevas Lukas Andrius, Gulacsi Alexandra, Horninger Wolfgang, Stuehmeier Jannik

Medical University Innsbruck, Department of Urology, 35 Anich Street, 6020, Innsbruck, Austria.

Urol Case Rep. 2020 May 25;33:101281. doi: 10.1016/j.eucr.2020.101281. eCollection 2020 Nov.

Intralesional mitomycin C after direct visual internal urethrotomy for recurrent urethral stricture disease in patients suboptimal for open urethroplasty is an established option. We report a case of urethro-cavernosal-spongiosal fistula after intralesional mitomycin C into an area of previous dorsal inlay urethroplasty. The patient presented with pus draining from the urethral meatus ten days after treatment. Sterile abscesses developed within the corporal and spongious bodies, draining freely into the urethra. Complete spontaneous healing followed short-term transurethral catheterization and antibiotic prophylaxis.

对于不适合开放性尿道成形术的复发性尿道狭窄疾病患者，直视下尿道内切开术后病灶内注射丝裂霉素C是一种既定的选择。我们报告了1例在先前背侧镶嵌尿道成形术区域病灶内注射丝裂霉素C后发生尿道海绵体瘘的病例。该患者在治疗10天后出现尿道口有脓液流出。阴茎海绵体和尿道海绵体内形成无菌性脓肿，并自行通畅地排入尿道。经短期经尿道置管和抗生素预防后，实现了完全自愈。