Desai Ninad M., Shah Sumir u.
Wyckoff Heights Medical Center
Orbital compartment syndrome (OCS) is caused due to rapidly increasing intra-orbital pressure and can lead to permanent blindness. OCS is a sight-threatening condition, originally described by Gordan and McRae in 1950 in a case following zygoma fracture repair. OCS is secondary to ischemia of the optic nerve and related retinal function, and a lack of perfusion can lead to irreversible loss of vision. OCS is a type of compartment syndrome, and as with other compartment syndromes, rapidly increasing intra-compartment pressures are related to significant morbidity and permanent damage. OCS occurs as a result of mass effect within the confines of the orbit; any process that can cause an increase in intraorbital pressure can lead to OCS. Intraorbital pressures can increase due to both hemorrhage and non-hemorrhagic processes, such as fluid accumulation. Non-traumatic causes of hemorrhage include iatrogenic procedures such as orbital, eyelid, and lacrimal surgeries. Orbital hemorrhage can also be caused by commonly used anesthetic procedures such as peribulbar or retrobulbar injections of localized anesthetics. Valsalva-related hemorrhage in the setting of sinonasal carcinoma, orbital-lymphatic malformation-related hemorrhages, extraocular tumors causing metastases has also been demonstrated as causes of OCS. Non-hemorrhagic causes of OCS include processes such as prolonged prone surgery (such as spinal surgery), facial and periocular burns, and massive fluid resuscitation for severe burns, all of which can lead to third-spacing of fluid within the orbital compartment. Uncommon causes of OCS include orbital emphysema in the setting of associated paranasal sinus fractures. All emergency physicians must also be wary of orbital cellulitis, regardless of the presence of an associated abscess, as a possible cause of OCS. OCS is a serious ophthalmologic emergency, regardless of etiology, and all emergency physicians should be able to clinically diagnose this condition and have an understanding of lateral orbital canthotomy and cantholysis (LOC) procedure in order help prevent permanent vision loss. OCS can lead to proptosis of the globe, which leads to stretch tension on the optic nerve in addition to the compressive forces of the intra-compartment pressure. The goal of LOC is to free the eyelid from its lateral attachment to the bony orbit, thus releasing the pressure that has accumulated within the closed orbital compartment. While emergent ophthalmologic consultation is ideal for intervention, optic nerve ischemia due to OCS can develop very rapidly. Improved visual outcomes can be achieved if interventions such as LOC are performed promptly (ideally within 2 hours of presentation).
眼眶间隔综合征(OCS)是由眶内压力迅速升高引起的,可导致永久性失明。OCS是一种威胁视力的疾病,最初由戈登和麦克雷于1950年在一例颧骨骨折修复后的病例中描述。OCS继发于视神经及相关视网膜功能的缺血,灌注不足可导致不可逆的视力丧失。OCS是间隔综合征的一种类型,与其他间隔综合征一样,间隔内压力迅速升高与严重的发病率和永久性损伤有关。OCS是由于眼眶范围内的占位效应而发生的;任何可导致眶内压力升高的过程都可导致OCS。眶内压力可因出血和非出血性过程(如液体蓄积)而升高。出血的非创伤性原因包括医源性操作,如眼眶、眼睑和泪腺手术。眼眶出血也可由常用的麻醉操作引起,如球周或球后注射局部麻醉剂。鼻窦癌相关的瓦尔萨尔瓦动作性出血、眼眶淋巴管畸形相关的出血、导致转移的眼外肿瘤也已被证明是OCS的病因。OCS的非出血性原因包括长时间俯卧位手术(如脊柱手术)、面部和眼周烧伤以及严重烧伤后的大量液体复苏等过程,所有这些都可导致眼眶间隔内液体的第三间隙分布。OCS的罕见原因包括相关鼻窦骨折时的眼眶气肿。所有急诊医生也必须警惕眼眶蜂窝织炎,无论是否存在相关脓肿,因为它可能是OCS的一个原因。OCS是一种严重的眼科急症,无论病因如何,所有急诊医生都应能够临床诊断这种疾病,并了解外侧眶切开术和眦切开术(LOC)操作,以帮助预防永久性视力丧失。OCS可导致眼球突出,这除了间隔内压力的压迫力外,还会对视神经产生拉伸张力。LOC的目的是将眼睑从其与眼眶骨的外侧附着处松解,从而释放积聚在封闭眼眶间隔内的压力。虽然紧急眼科会诊是理想的干预方式,但OCS导致的视神经缺血发展非常迅速。如果及时进行LOC等干预措施(理想情况下在就诊后2小时内),可以实现更好的视力预后。