Laboratory of Veterinary Internal Medicine, Department of Clinical Sciences, Faculty of Veterinary Medicine, Hokkaido University, Kita 18-jo Nishi 9-chome, Kita-ku, Sapporo 060-0818, Japan.
Veterinary Teaching Hospital, Faculty of Veterinary Medicine, Hokkaido University, Kita 18-jo Nishi 10-chome, Kita-ku, Sapporo 060-0819, Japan.
J Vet Med Sci. 2020 Jul 31;82(7):1012-1016. doi: 10.1292/jvms.20-0183. Epub 2020 Jun 4.
The feasibility of ultrasonographic measurement of thyroid gland area to common carotid artery (TG:CCA) was investigated. Twenty-one healthy, 12 hypothyroid and 18 non-thyroid illness (NTI) dogs were evaluated. The area of thyroid lobe and common carotid artery in right and left sides were measured using the same ultrasonographic images in transverse plane. The average of the right and left ratio was calculated as TG:CCA. The median TG:CCA of 21 healthy dogs was 1.53, and it did not correlate either body weight or age. The median TG:CCA of 12 hypothyroid dogs was 0.81, which was significantly lower than that of 18 NTI dogs (1.81, P<0.001). If the cut off value <1.12 was used, TG:CCA indicated hypothyroidism with a sensitivity of 100%, specificity of 83%, and accuracy of 90%. Our data indicated that TG:CCA was independent of both body weight, which may contribute to consistent measurement of thyroid size. The results of this study suggest that TG:CCA is a promising tool for diagnosing canine hypothyroidism.
本研究旨在探讨甲状腺面积与颈总动脉（TG:CCA）比值超声测量在甲状腺疾病诊断中的可行性。21 只健康犬、12 只甲状腺功能减退症（简称甲减）犬和 18 只非甲状腺疾病（简称 NTI）犬被纳入研究。使用横断面超声图像测量双侧甲状腺叶和颈总动脉面积，计算右、左两侧的平均值作为 TG:CCA。21 只健康犬的 TG:CCA 中位数为 1.53，与体重或年龄均无相关性。12 只甲减犬的 TG:CCA 中位数为 0.81，显著低于 18 只 NTI 犬（1.81，P<0.001）。如果截断值<1.12，TG:CCA 对甲减的敏感度为 100%，特异度为 83%，准确度为 90%。本研究表明，TG:CCA 不依赖于体重，可能有助于甲状腺大小的一致性测量。研究结果提示，TG:CCA 是诊断犬甲减的一种有前途的工具。
