GPR84: an immune response dial?
作者信息
Wojciechowicz Megan L, Ma'ayan Avi
出版信息
Nat Rev Drug Discov. 2020 Jun;19(6):374. doi: 10.1038/d41573-020-00029-9.
Abstract
摘要
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本文引用的文献
1
An Agonist Radioligand for the Proinflammatory Lipid-Activated G Protein-Coupled Receptor GPR84 Providing Structural Insights.一种激动剂放射性配体，用于促炎脂质激活的 G 蛋白偶联受体 GPR84，提供结构见解。
J Med Chem. 2020 Mar 12;63(5):2391-2410. doi: 10.1021/acs.jmedchem.9b01339. Epub 2019 Nov 27.
2
A Biased Agonist at Immunometabolic Receptor GPR84 Causes Distinct Functional Effects in Macrophages.免疫代谢受体 GPR84 的偏性激动剂在巨噬细胞中引起不同的功能效应。
ACS Chem Biol. 2019 Sep 20;14(9):2055-2064. doi: 10.1021/acschembio.9b00533. Epub 2019 Sep 10.
3
Regulation of mitochondrial metabolism in murine skeletal muscle by the medium-chain fatty acid receptor Gpr84.Gpr84 介导的长链脂肪酸受体调控小鼠骨骼肌中线粒体代谢
FASEB J. 2019 Nov;33(11):12264-12276. doi: 10.1096/fj.201900234R. Epub 2019 Aug 15.
4
A Newly Discovered Antifibrotic Pathway Regulated by Two Fatty Acid Receptors: GPR40 and GPR84.两种脂肪酸受体（GPR40 和 GPR84）调控的新发现抗纤维化途径。
Am J Pathol. 2018 May;188(5):1132-1148. doi: 10.1016/j.ajpath.2018.01.009. Epub 2018 Feb 16.
5
Medium-chain fatty acid-sensing receptor, GPR84, is a proinflammatory receptor.中链脂肪酸感应受体 GPR84 是一种促炎受体。
J Biol Chem. 2013 Apr 12;288(15):10684-91. doi: 10.1074/jbc.M112.420042. Epub 2013 Feb 28.
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