疫苗免疫力下降导致的季节性末期医院内流感暴发。
End-of-season outbreaks of nosocomial influenza caused by waning vaccine immunity.
作者信息
Matsushita Masahide, Arise Kazumi, Morimoto Norihito, Takeuchi Seisho
机构信息
Department of Family Medicine, Kochi Medical School, Nankoku, Japan.
Department of Infection Control and Prevention, Kochi Medical School Hospital, Nankoku, Japan.
出版信息
J Infect Prev. 2020 May;21(3):119-121. doi: 10.1177/1757177420908012. Epub 2020 May 4.
Abstract
The waning of vaccine protection may be responsible for outbreaks toward the end of the influenza season. Three of five outbreaks occurred at the beginning of April following an interval of >100 days from the date of vaccination; the reported index case was a nurse or office worker, and >50% of those affected were healthcare workers. The results are consistent with intra-seasonal waning of vaccine immunity that resulted in outbreaks at the end of season.
摘要
疫苗保护作用的减弱可能是流感季节末期爆发疫情的原因。五起疫情中有三起发生在4月初，自接种疫苗之日起间隔超过100天；报告的首例病例是一名护士或办公室工作人员，且受影响者中超过50%是医护人员。这些结果与疫苗免疫力在季节内减弱导致季节末爆发疫情的情况相符。
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