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原发性小儿小脑胶质肉瘤。

Primary pediatric cerebellar gliosarcoma.

作者信息

Bukhari Syed Sarmad, Junaid Muhammad, Afzal Ali, Kulsoom Anisa

机构信息

Department of Neurosurgery, Aga Khan University Hospital, Karachi, Pakistan.

Department of Neurosurgery, Bahria University Medical and Dental College, Karachi, Pakistan.

出版信息

Surg Neurol Int. 2020 May 9;11:96. doi: 10.25259/SNI_274_2019. eCollection 2020.

DOI:10.25259/SNI_274_2019
PMID:32494375
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7265428/
Abstract

BACKGROUND

Primary gliosarcomas of the central nervous are rare and very few have been reported in the infratentorial compartment. Here, we describe such a lesion in a 12-year-old male.

CASE DESCRIPTION

A 12-year-old male presented with headache, ataxia, and vomiting. When Magnetic resonance studies documented a posterior fossa lesion, he underwent placement of a right ventriculoperitoneal shunt followed by a suboccipital craniectomy. The lesion proved to be a primary gliosarcoma. Unfortunately, it recurred 2 years later and required repeated resection.

CONCLUSION

Here, we reviewed the rare case of a 12-year-old male requiring shunt placement and suboccipital craniectomy for a primary gliosarcoma that recurred 2 years later.

摘要

背景

中枢神经系统原发性胶质肉瘤罕见,幕下区域报道的病例极少。在此,我们描述一名12岁男性的此类病变。

病例描述

一名12岁男性出现头痛、共济失调和呕吐症状。磁共振检查发现后颅窝有病变后,他接受了右心室 - 腹腔分流术,随后进行了枕下颅骨切除术。病变证实为原发性胶质肉瘤。不幸的是,2年后肿瘤复发,需要再次切除。

结论

在此,我们回顾了这例罕见病例,一名12岁男性因原发性胶质肉瘤接受分流术和枕下颅骨切除术,2年后肿瘤复发。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b769/7265428/e491424b8058/SNI-11-96-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b769/7265428/f5bcab0b0efa/SNI-11-96-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b769/7265428/c130d36f9d30/SNI-11-96-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b769/7265428/2094bb4eb2b3/SNI-11-96-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b769/7265428/1fe91e55857d/SNI-11-96-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b769/7265428/e491424b8058/SNI-11-96-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b769/7265428/f5bcab0b0efa/SNI-11-96-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b769/7265428/c130d36f9d30/SNI-11-96-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b769/7265428/2094bb4eb2b3/SNI-11-96-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b769/7265428/1fe91e55857d/SNI-11-96-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b769/7265428/e491424b8058/SNI-11-96-g005.jpg

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引用本文的文献

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2
Gliosarcoma in patients under 20 years of age. A clinicopathologic study of 11 cases and detailed review of the literature.20 岁以下患者的胶质肉瘤。11 例临床病理研究及文献复习。
BMC Pediatr. 2021 Feb 26;21(1):101. doi: 10.1186/s12887-021-02556-9.

本文引用的文献

1
Primary Cerebellar Gliosarcoma with Extracranial Metastases: An Orphan Differential Diagnosis.伴有颅外转移的原发性小脑胶质肉瘤:一种罕见的鉴别诊断。
World Neurosurg. 2015 Dec;84(6):2076.e13-7. doi: 10.1016/j.wneu.2015.07.049. Epub 2015 Jul 31.
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Pediatric gliosarcoma of thalamus.
Neurol India. 2012 Nov-Dec;60(6):674-6. doi: 10.4103/0028-3886.105222.
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Clinical and epidemiological characteristics of pediatric gliosarcomas.儿童胶质肉瘤的临床和流行病学特征。
J Neurooncol. 2010 Apr;97(2):257-65. doi: 10.1007/s11060-009-0021-3. Epub 2009 Oct 6.
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Primary gliosarcoma: key clinical and pathologic distinctions from glioblastoma with implications as a unique oncologic entity.原发性神经胶质肉瘤:与胶质母细胞瘤的关键临床和病理区别及其作为独特肿瘤实体的意义。
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Gliosarcoma with osteosarcomatous differentiation: review of radiological and pathological features.具有骨肉瘤样分化的胶质肉瘤:放射学和病理学特征综述
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Gliosarcoma occurring 8 years after treatment for a medulloblastoma.髓母细胞瘤治疗8年后发生的胶质肉瘤。
Childs Nerv Syst. 2004 Apr;20(4):243-6. doi: 10.1007/s00381-003-0850-x. Epub 2003 Dec 24.
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Genetic profile of gliosarcomas.胶质肉瘤的基因图谱。
Am J Pathol. 2000 Feb;156(2):425-32. doi: 10.1016/S0002-9440(10)64746-3.
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Gliosarcoma of the posterior cranial fossa: MRI findings.
Neuroradiology. 1993;35(4):279-80. doi: 10.1007/BF00602614.