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使用基质标测对源自右心室下基底瘢痕的缺血性室性心动过速进行导管消融:病例报告

Catheter Ablation of Ischemic Ventricular Tachycardia Originating from an Inferobasal Right Ventricular Scar Using Substrate Mapping: A Case Report.

作者信息

Sohinki Daniel A, Nakagawa Hiroshi, Stavrakis Stavros

机构信息

Department of Cardiology, University of Oklahoma Health Sciences Center, Oklahoma City, OK, USA.

Heart Rhythm Institute, University of Oklahoma Health Sciences Center, Oklahoma City, OK, USA.

出版信息

J Innov Card Rhythm Manag. 2018 Jun 15;9(6):3207-3211. doi: 10.19102/icrm.2018.090604. eCollection 2018 Jun.

DOI:10.19102/icrm.2018.090604
PMID:32494496
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7252808/
Abstract

Catheter ablation of ventricular tachycardia (VT) has emerged as a superior alternative to antiarrhythmic drug therapy in patients with ischemic cardiomyopathy, with the vast majority of ischemic VT being ablation from the endocardial surface of the left ventricle (LV). While rare, the possibility of ischemic right ventricular (RV) VT should also be entertained, especially in patients with previous myocardial infarction and in those individuals in whom LV endocardial ablation fails to abolish VT. Further, success rates remain disappointing in some of these cases, often owing to difficulties in mapping the tachycardia due to hemodynamic instability during VT. We report a case of hemodynamically unstable ischemic VT successfully ablated from the endocardial surface of the LV and RV using a substrate mapping approach in a patient with a large inferior myocardial infarction, involving RV infarction.

摘要

在缺血性心肌病患者中,导管消融室性心动过速(VT)已成为抗心律失常药物治疗的一种更优替代方案,绝大多数缺血性VT是从左心室(LV)的心内膜表面进行消融。虽然缺血性右心室(RV)VT较为罕见,但也应予以考虑,尤其是在既往有心肌梗死的患者以及左心室心内膜消融未能消除VT的个体中。此外,在其中一些病例中成功率仍然令人失望,这通常是由于VT期间血流动力学不稳定导致心动过速标测困难。我们报告一例血流动力学不稳定的缺血性VT病例,该病例通过基质标测方法成功地从一名患有大面积下壁心肌梗死(累及右心室梗死)患者的左心室和右心室心内膜表面进行了消融。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b33c/7252808/821122b1fc12/icrm-09-3207-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b33c/7252808/eb4a0e0def77/icrm-09-3207-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b33c/7252808/9e75b5b562a7/icrm-09-3207-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b33c/7252808/821122b1fc12/icrm-09-3207-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b33c/7252808/eb4a0e0def77/icrm-09-3207-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b33c/7252808/9e75b5b562a7/icrm-09-3207-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b33c/7252808/821122b1fc12/icrm-09-3207-g003.jpg

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本文引用的文献

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Substrate Ablation of Ventricular Tachycardia: Late Potentials, Scar Dechanneling, Local Abnormal Ventricular Activities, Core Isolation, and Homogenization.室性心动过速的基质消融:晚电位、瘢痕去通道化、局部心室活动异常、核心隔离及均质化
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Characterization of the epicardial substrate for catheter ablation of Brugada syndrome.Brugada综合征导管消融的心外膜基质特征
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Ventricular Tachycardia Ablation versus Escalation of Antiarrhythmic Drugs.
室性心动过速消融与抗心律失常药物升级。
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J Am Coll Cardiol. 2016 Feb 16;67(6):684-686. doi: 10.1016/j.jacc.2015.10.095.
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Ventricular tachycardia in ischemic cardiomyopathy; a combined endo-epicardial ablation as the first procedure versus a stepwise approach (EPILOGUE) - study protocol for a randomized controlled trial.缺血性心肌病中的室性心动过速;首次采用心内膜-心外膜联合消融术与逐步治疗方法(EPILOGUE)——一项随机对照试验的研究方案
Trials. 2015 Oct 29;16:487. doi: 10.1186/s13063-015-1005-6.
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The challenges in the management of right ventricular infarction.右心室梗死的处理难点。
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Elimination of local abnormal ventricular activities: a new end point for substrate modification in patients with scar-related ventricular tachycardia.消除局部异常心室活动:瘢痕相关室性心动过速患者基质修饰的新终点。
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