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右半活体肝移植术后患者人造血管移植物进入中空内脏器官。

Artificial vascular graft migration into hollow viscus organs in patients who underwent right lobe living donor liver transplantation.

机构信息

Liver Transplant Institute, Inonu University, Malatya, Turkey.

Department of Gastroenterology, Faculty of Medicine, Inonu University, Malatya, Turkey.

出版信息

Acta Chir Belg. 2020 Dec;120(6):404-412. doi: 10.1080/00015458.2020.1778266. Epub 2020 Jun 22.

Abstract

BACKGROUND

To share our experience with hollow viscus migration of artificial vascular grafts (AVG) used for venous reconstruction of the right anterior sector in living donor liver transplantations (LDLT).

METHODS

Clinical, radiological, and endoscopic data of 13 right lobe LDLT patients (range: 26-67 years) with a diagnosis of postoperative AVG migration into adjacent hollow viscus were analyzed.

RESULTS

Biliary complications were detected in 12 patients. A median of four times endoscopic retrograde cholangiopancreatography (ERCP) procedures were performed in 11 patients prior to AVG migration diagnosis. A median of 2.5 times various percutaneous radiological interventional procedures were performed in eight patients prior to AVG migration diagnosis. The site of migration was the duodenum in eight patients, gastric antrum in four, and Roux limb in the remaining one patient. The migrated AVS were made of polytetrafluoroethylene (PTFE) in 10 patients and polyethylene terephthalate (Dacron) in three. The migrated AVGs were endoscopically removed in seven patients and surgically removed in six. Only one patient died due to sepsis unrelated to AVG migration.

CONCLUSION

AVG migration into the adjacent hollow viscus following right lobe LDLT is a rare and serious complication. Repetitive ERCP, interventional radiological procedures, infection related to biliary leakage, and thrombosis of AVGs are among the possible risk factors.

摘要

背景

分享我们在活体肝移植(LDLT)中右前区静脉重建中使用人工血管移植物(AVG)发生空心内脏迁移的经验。

方法

分析了 13 例右叶 LDLT 患者(年龄 26-67 岁)术后诊断为 AVG 迁移至相邻空心内脏的临床、放射学和内镜数据。

结果

12 例患者发现胆系并发症。11 例患者在诊断 AVG 迁移前平均进行了 4 次内镜逆行胰胆管造影(ERCP)检查。8 例患者在诊断 AVG 迁移前平均进行了 2.5 次各种经皮放射介入治疗。8 例患者的迁移部位为十二指肠,4 例为胃窦,1 例为 Roux 支。10 例移植物为聚四氟乙烯(PTFE),3 例为聚对苯二甲酸乙二醇酯(Dacron)。7 例患者经内镜取出移植物,6 例患者经手术取出移植物。仅 1 例患者因与 AVG 迁移无关的败血症死亡。

结论

右叶 LDLT 后 AVG 迁移至相邻空心内脏是一种罕见且严重的并发症。重复 ERCP、介入放射学程序、与胆漏相关的感染和 AVG 血栓形成是可能的危险因素之一。

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