Department of Dermatology, American University of Beirut Medical Center, Beirut, Lebanon.
Department of Dermatology, American University of Beirut Medical Center, Beirut, Lebanon.
J Am Acad Dermatol. 2022 Sep;87(3):614-622. doi: 10.1016/j.jaad.2020.05.113. Epub 2020 Jun 1.
The genital skin may be affected by a variety of dermatoses, be it inflammatory, infectious, malignant, idiopathic, or others. The red scrotum syndrome is characterized by persistent erythema of the scrotum associated with a burning sensation, hyperalgesia, and itching. Its cause is unknown, but proposed mechanisms include rebound vasodilation after prolonged topical corticosteroid use and localized erythromelalgia. The condition is chronic, and treatment is often difficult. Here we review the etiology, the physical and histopathologic findings, and the management of this condition. We also describe related conditions such as red scalp syndrome, red ear syndrome, and red vulva syndrome. Finally, we summarize the different cases reported in the literature and discuss the features that help in the differentiation of red scrotum syndrome from its mimickers.
生殖器皮肤可能受到各种皮肤病的影响，包括炎症性、感染性、恶性、特发性或其他疾病。红斑阴囊综合征的特征是阴囊持续红斑，伴有烧灼感、触痛和瘙痒。其病因不明，但提出的机制包括长期局部使用皮质类固醇后反弹性血管扩张和局部性红痛。这种情况是慢性的，治疗通常很困难。在这里，我们回顾了这种情况的病因、临床表现和组织病理学表现以及治疗方法。我们还描述了相关疾病，如红斑头皮综合征、红斑耳综合征和红斑外阴综合征。最后，我们总结了文献中报道的不同病例，并讨论了有助于将红斑阴囊综合征与其类似疾病区分开来的特征。
