COVID-19 疫情时期的 NSAIDs 类药物用于镇痛。
NSAIDs for analgesia in the era of COVID-19.
机构信息
Department of Anesthesiology and Pain Medicine, Detroit Medical Center/Wayne State University, Detroit, Michigan, USA
Department of Emergency Medicine, MedStar Georgetown University Hospital, Washington, District of Columbia, USA.
出版信息
Reg Anesth Pain Med. 2020 Sep;45(9):677-678. doi: 10.1136/rapm-2020-101584. Epub 2020 Jun 3.
Abstract
Globally, non-steroidal anti-inflammatory drugs (NSAIDs) are highly used to treat pain. With the rise of the COVID-19 pandemic, the safety of NSAIDs use has been called into question. These concerns are worthy of review. At present, there is no compelling data showing that NSAIDs worsen the severity of COVID-19 symptoms or increase one's likelihood of contracting the illness. For patients in pain and without symptoms that could potentially be attributed to COVID-19 (cough, fevers/chills, lethargy, myalgias, anosmia and so on), NSAIDs should continue to remain a viable option to provide analgesia to patients in need.
摘要
在全球范围内，非甾体抗炎药（NSAIDs）被广泛用于治疗疼痛。随着 COVID-19 大流行的出现，人们对 NSAIDs 使用的安全性提出了质疑。这些担忧值得我们进行审查。目前，没有确凿的数据表明 NSAIDs 会加重 COVID-19 症状的严重程度或增加感染的可能性。对于那些有疼痛但没有可能归因于 COVID-19 的症状（咳嗽、发热/发冷、乏力、肌痛、嗅觉丧失等）的患者，NSAIDs 仍然是为有需要的患者提供镇痛的可行选择。
相似文献
1
NSAIDs for analgesia in the era of COVID-19.COVID-19 疫情时期的 NSAIDs 类药物用于镇痛。
Reg Anesth Pain Med. 2020 Sep;45(9):677-678. doi: 10.1136/rapm-2020-101584. Epub 2020 Jun 3.
2
COVID-19 and NSAIDs: Primum non nocere.2019冠状病毒病与非甾体抗炎药：首要的是不伤害。
Therapie. 2020 Sep-Oct;75(5):514-515. doi: 10.1016/j.therap.2020.07.008. Epub 2020 Jul 22.
3
NSAIDs may increase the risk of thrombosis and acute renal failure in patients with COVID-19 infection.非甾体抗炎药（NSAIDs）可能会增加新型冠状病毒肺炎（COVID-19）感染患者发生血栓形成和急性肾衰竭的风险。
Therapie. 2020 Jul-Aug;75(4):387-388. doi: 10.1016/j.therap.2020.06.012. Epub 2020 Jun 27.
4
Covid-19-The real role of NSAIDs in Italy.新冠疫情——非甾体抗炎药在意大利的实际作用
J Orthop Surg Res. 2020 May 4;15(1):165. doi: 10.1186/s13018-020-01682-x.
5
Adverse outcomes and mortality in users of non-steroidal anti-inflammatory drugs who tested positive for SARS-CoV-2: A Danish nationwide cohort study.感染 SARS-CoV-2 的非甾体抗炎药使用者的不良结局和死亡率：一项丹麦全国队列研究。
PLoS Med. 2020 Sep 8;17(9):e1003308. doi: 10.1371/journal.pmed.1003308. eCollection 2020 Sep.
6
Warning Against the Use of Anti-Inflammatory Medicines to Cure COVID-19: Building Castles in the Air.警告：切勿使用抗炎药物治疗新冠病毒病：此举无异于空中楼阁。
Adv Ther. 2020 May;37(5):1705-1707. doi: 10.1007/s12325-020-01321-1. Epub 2020 Apr 1.
7
NSAIDs in patients with viral infections, including Covid-19: Victims or perpetrators?病毒感染患者（包括新冠病毒）中使用 NSAIDs：是受害者还是肇事者？
Pharmacol Res. 2020 Jul;157:104849. doi: 10.1016/j.phrs.2020.104849. Epub 2020 Apr 29.
8
[Not Available].[无可用内容]。
MMW Fortschr Med. 2020 Apr;162(7):18-20. doi: 10.1007/s15006-020-0372-4.
9
[Drugs that aggravate the course of COVID-19 : really ?].[加重新型冠状病毒肺炎病程的药物：真的吗？]
Rev Med Suisse. 2020 Apr 29;16(N° 691-2):852-854.
10
Managing chronic pain patients at the time of COVID-19 pandemic.在2019冠状病毒病大流行期间管理慢性疼痛患者。
Minerva Anestesiol. 2020 Aug;86(8):797-799. doi: 10.23736/S0375-9393.20.14666-2. Epub 2020 May 12.
引用本文的文献
1
Pain Management Providers in the Era of COVID-19: Who is Taking Care of Those Who Provide Care?新冠疫情时代的疼痛管理提供者：谁来照顾那些提供护理的人？
J Pain Res. 2022 Jan 11;15:67-70. doi: 10.2147/JPR.S356744. eCollection 2022.
2
Practical recommendations for the management of the patient with chronic pain during the pandemic of COVID-19.2019冠状病毒病大流行期间慢性疼痛患者管理的实用建议。
Rev Esp Anestesiol Reanim (Engl Ed). 2020 Sep 2;68(9):495-503. doi: 10.1016/j.redar.2020.08.005.
3
[Not Available].[无可用内容]
FMC. 2021 Mar;28(3):191-201. doi: 10.1016/j.fmc.2021.01.006. Epub 2021 Mar 23.
4
The Coronaviruses of Animals and Birds: Their Zoonosis, Vaccines, and Models for SARS-CoV and SARS-CoV2.动物和鸟类的冠状病毒：它们的人畜共患病、疫苗以及严重急性呼吸综合征冠状病毒和严重急性呼吸综合征冠状病毒2的模型
Front Vet Sci. 2020 Sep 24;7:582287. doi: 10.3389/fvets.2020.582287. eCollection 2020.
5
Second Update for Anaesthetists on Clinical Features of COVID-19 Patients and Relevant Management.麻醉医生关于COVID-19患者临床特征及相关管理的第二次更新
J Clin Med. 2020 Aug 6;9(8):2542. doi: 10.3390/jcm9082542.
本文引用的文献
1
Safety of Ibuprofen in Patients With COVID-19: Causal or Confounded?布洛芬在新冠病毒肺炎患者中的安全性：因果关系还是混淆因素？
Chest. 2020 Jul;158(1):55-56. doi: 10.1016/j.chest.2020.03.040. Epub 2020 Mar 31.
2
Warning Against the Use of Anti-Inflammatory Medicines to Cure COVID-19: Building Castles in the Air.警告：切勿使用抗炎药物治疗新冠病毒病：此举无异于空中楼阁。
Adv Ther. 2020 May;37(5):1705-1707. doi: 10.1007/s12325-020-01321-1. Epub 2020 Apr 1.
3
Non-steroidal anti-inflammatory drugs and covid-19.非甾体抗炎药与新冠病毒病
BMJ. 2020 Mar 27;368:m1185. doi: 10.1136/bmj.m1185.
4
Covid-19: European drugs agency to review safety of ibuprofen.新冠疫情：欧洲药品管理局将审查布洛芬的安全性。
BMJ. 2020 Mar 23;368:m1168. doi: 10.1136/bmj.m1168.
5
Are patients with hypertension and diabetes mellitus at increased risk for COVID-19 infection?高血压和糖尿病患者感染新型冠状病毒肺炎（COVID-19）的风险会增加吗？
Lancet Respir Med. 2020 Apr;8(4):e21. doi: 10.1016/S2213-2600(20)30116-8. Epub 2020 Mar 11.
6
Receptor Recognition by the Novel Coronavirus from Wuhan: an Analysis Based on Decade-Long Structural Studies of SARS Coronavirus.新型冠状病毒受体识别：基于 SARS 冠状病毒长达十年结构研究的分析。
J Virol. 2020 Mar 17;94(7). doi: 10.1128/JVI.00127-20.
7
Efficacy of Clarithromycin-Naproxen-Oseltamivir Combination in the Treatment of Patients Hospitalized for Influenza A(H3N2) Infection: An Open-label Randomized, Controlled, Phase IIb/III Trial.克拉霉素-萘普生-奥司他韦联合用药治疗甲型（H3N2）流感感染住院患者的疗效：一项开放标签随机对照IIb/III期试验
Chest. 2017 May;151(5):1069-1080. doi: 10.1016/j.chest.2016.11.012. Epub 2016 Nov 22.
8
Nonsteroidal Anti-Inflammatory Drug and Aspirin Use, and Mortality among Critically Ill Pandemic H1N1 Influenza Patients: an Exploratory Analysis.非甾体抗炎药和阿司匹林的使用与重症甲型H1N1流感患者死亡率的探索性分析
Jpn J Infect Dis. 2016 May 20;69(3):248-51. doi: 10.7883/yoken.JJID.2014.577. Epub 2015 Aug 7.
9
Influence of morphine on host immunity.吗啡对宿主免疫的影响。
Acta Anaesthesiol Taiwan. 2011 Sep;49(3):105-8. doi: 10.1016/j.aat.2011.08.003. Epub 2011 Sep 22.
10
Should nonsteroidal anti-inflammatory drugs (NSAIDs) be prescribed to the older adult?老年人是否应该开非甾体抗炎药（NSAIDs）？
Drugs Aging. 2010 Oct 1;27(10):775-89. doi: 10.2165/11539430-000000000-00000.
Zotero 插件