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COVID-19 疫苗:中和抗体与铝佐剂的优势。

COVID-19 vaccines: neutralizing antibodies and the alum advantage.

机构信息

Texas Children's Center for Vaccine Development, Houston, TX, USA.

Departments of Pediatrics and Molecular Virology and Microbiology, National School of Tropical Medicine, Baylor College of Medicine, Houston, TX, USA.

出版信息

Nat Rev Immunol. 2020 Jul;20(7):399-400. doi: 10.1038/s41577-020-0358-6.

Abstract

Achieving high levels of neutralizing antibodies to the spike protein of SARS-CoV-2 in a safe manner is likely to be crucial for an effective vaccine. Here, we propose that aluminium-based adjuvants might hold the key to this.

摘要

以安全的方式实现对 SARS-CoV-2 刺突蛋白的高水平中和抗体可能是有效疫苗的关键。在这里,我们提出铝基佐剂可能是关键。

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