Eskandari Delaram, Khodabandehloo Niloofar, Gholami Abbas, Samadanifard Hosein, Hejrati Alireza
Department of endocrinology, School of Medicine, Hazrat-e Rasool Hospital, Iran University of Medical Sciences. Tehran, Iran.
School of Medicine, Hazrat-e Rasool Hospital, Iran University of Medical Sciences. Tehran, Iran.
Eur J Transl Myol. 2020 Apr 1;30(1):8776. doi: 10.4081/ejtm.2019.8776. eCollection 2020 Apr 7.
One of the most serious cancers among women is breast cancer. This disease is the first reason for the death of women due to cancer. Increasing breast cancer risk may associate with many factors including genetic, reproductive factors, people's lifestyle, metabolic syndrome (MS) and hormones. MS has been known as a risk factor for prostate, pancreatic, breast and colorectal cancers. The purpose of this review is to identify the relationship between MS components and breast cancer individually. This study was performed by researching electronic database references including PubMed, Google Scholar, CINAHL ProQuest, and web of science through 2019. The effect of MS with its components and breast cancer was reported in many studies. Nevertheless, a thorough understanding of the mechanisms involved remains a challenge. However, one can take several preventive measures, including a proper diet, which is one of the most important determinants of metabolic status. Also, general preventive recommendations are including reducing alcohol consumption, red meat and total fat in the diet. Moreover, increasing the consumption of vegetable and fruit reduce the proportion of MS patients to improve the outcome of breast cancer patients.
女性中最严重的癌症之一是乳腺癌。这种疾病是女性因癌症死亡的首要原因。乳腺癌风险增加可能与许多因素有关，包括遗传、生殖因素、人们的生活方式、代谢综合征（MS）和激素。MS已被认为是前列腺癌、胰腺癌、乳腺癌和结直肠癌的一个风险因素。本综述的目的是分别确定MS各组成部分与乳腺癌之间的关系。本研究通过检索包括PubMed、谷歌学术、CINAHL ProQuest和科学网在内的电子数据库参考文献进行，检索时间截至2019年。许多研究报告了MS及其组成部分与乳腺癌的关系。然而，对其中涉及的机制进行全面了解仍然是一项挑战。不过，人们可以采取多种预防措施，包括合理饮食，这是代谢状态最重要的决定因素之一。此外，一般预防建议包括减少酒精摄入、减少饮食中的红肉和总脂肪。此外，增加蔬菜和水果的摄入量可降低MS患者的比例，从而改善乳腺癌患者的预后。
