Eggerstedt Michael, Dua Sumeet G, Varelas Antonios N, Bhabad Sudeep H, Batra Pete S, Tajudeen Bobby A
Department of Otorhinolaryngology - Head and Neck Surgery, Rush Sinus Program, Rush University Medical Center, Chicago, Illinois, United States.
Department of Radiology, Rush University Medical Center, Chicago, Illinois, United States.
J Neurol Surg B Skull Base. 2020 Jun;81(3):232-236. doi: 10.1055/s-0039-1688783. Epub 2019 May 3.
The objective of this study is to compare the visibility and size of Dorello's canal (DC) on magnetic resonance imaging between patients with idiopathic intracranial hypertension (IIH) and control patients, for its evaluation as a potential novel marker for chronic increased intracranial pressure (ICP). Retrospective blinded case-control study. Tertiary care academic center. Fourteen patients with spontaneous cerebrospinal fluid (CSF) rhinorrhea and diagnosed IIH, as well as an equal number of age and gender-matched controls. Radiographic presence or absence of visible CSF sleeve within DC as well as CSF sleeve width when present. Following review of 28 IIH canals and 28 control canals, IIH patients were significantly more likely to have a visible CSF sleeve within DC and to have a wider measured medial entrance to DC ( < 0.001). Identification of CSF evagination into DC may serve as a reliable marker for increased ICP in the IIH population. This finding should be considered in the future as paradigms for diagnosis of IIH continue to evolve.
本研究的目的是比较特发性颅内高压（IIH）患者与对照患者在磁共振成像上Dorello管（DC）的可视性和大小，以评估其作为慢性颅内压（ICP）升高的潜在新标志物。 回顾性盲法病例对照研究。 三级医疗学术中心。 14例自发性脑脊液（CSF）鼻漏并诊断为IIH的患者，以及数量相等的年龄和性别匹配的对照。 DC内可见CSF袖套的影像学表现及存在时CSF袖套的宽度。 在对28条IIH管和28条对照管进行评估后，IIH患者在DC内出现可见CSF袖套以及测量的DC内侧入口更宽的可能性显著更高（ <0.001）。 识别CSF向DC内的突出可能是IIH人群中ICP升高的可靠标志物。随着IIH诊断范式的不断发展，这一发现未来应予以考虑。
