Wilkinson P J, Ball A J, Doran J, Gillespie W A, Orton V S
J Clin Pathol. 1977 May;30(5):417-20. doi: 10.1136/jcp.30.5.417.
Postoperative chest infection was studied prospectively in 73 patients in order to evaluate standard laboratory methods of sputum examination and to relate the results to the patients' clinical state and to antibiotic therapy. When a culture medium selective for haemophilus was used in addition to unselective media, homogenisation of the specimen gave no advantage. Laboratory and clinical findings usually corresponded well. Profuse growths of Streptococcus pneumoniae or Haemophilus influenzae were clearly associated with clinical evidence of chest infection but other Gramnegative bacilli and Staphylococcus aureus much less so. Coliforms were more prominent after antibiotic therapy.
对73例患者进行了术后胸部感染的前瞻性研究，以评估痰液检查的标准实验室方法，并将结果与患者的临床状况及抗生素治疗相关联。除了非选择性培养基外，当使用对嗜血杆菌有选择性的培养基时，标本匀化并无优势。实验室检查结果与临床情况通常吻合良好。肺炎链球菌或流感嗜血杆菌的大量生长与胸部感染的临床证据明显相关，而其他革兰氏阴性杆菌和金黄色葡萄球菌则相关性小得多。抗生素治疗后大肠菌群更为突出。
