Kanzelmeyer Nele K, Lerch Christian, Ahlenstiel-Grunow Thurid, Bräsen Jan H, Haffner Dieter, Pape Lars
Department of Pediatric Nephrology.
Department of Pathology, Hannover Medical School, Hannover, Germany.
Medicine (Baltimore). 2020 Jun 5;99(23):e20522. doi: 10.1097/MD.0000000000020522.
Data on protocol biopsies (PBs) after pediatric kidney transplantation are rare.We evaluated 6-month post-transplantation renal function in 86 children after PB as observational study. Patients were divided into 3 groups:Glomerular filtration rate (GFR) and delta GFR were determined.PBs 6 months post-kidney transplantation did not influence the clinical course in stable pediatric patients and are therefore of questionable value. Decreased kidney function may however be stabilized by therapeutic intervention according to results of PB.
小儿肾移植后经 protocol 活检（PB）的数据很少见。作为一项观察性研究，我们评估了 86 例儿童在 PB 后 6 个月的移植肾功能。患者分为 3 组：测定肾小球滤过率（GFR）和 GFR 变化值。肾移植后 6 个月的 PB 对病情稳定的小儿患者的临床病程没有影响，因此其价值存疑。然而，根据 PB 的结果进行治疗干预可能会稳定肾功能下降的情况。
