Department of Forensic Medicine, All India Institute of Medical Sciences (AIIMS), Batinda, India.
Department of Forensic Medicine, All India Institute of Medical Sciences (AIIMS), Nagpur, India.
Med Leg J. 2020 Sep;88(3):160-162. doi: 10.1177/0025817220926928. Epub 2020 Jun 5.
Toxic epidermal necrolysis is a rapidly progressive exfoliating dermatosis which simulates second degree burns. The authors describe a fatal case reported as due to burns. Around 95% of the deceased's total body surface area was affected, with epidermolysis over face, chest, abdomen, limbs and associated with mucosal involvement. Histopathological findings revealed epidermal necrolysis and confirmed the autopsy suspicion. Because of its sudden onset and rapid progression, toxic epidermal necrolysis often arises suspicion of burns by investigators. We emphasise the differentiating features between toxic epidermal necrolysis and burns and its implications.
中毒性表皮坏死松解症是一种迅速进展的剥脱性皮炎，类似于二度烧伤。作者描述了一例报告为烧伤导致的致死病例。死者约 95%的全身表面积受到影响，面部、胸部、腹部、四肢均有表皮松解，伴有粘膜受累。组织病理学发现为表皮坏死松解，证实了尸检的推测。由于其突然发作和迅速进展，中毒性表皮坏死松解症常引起调查人员对烧伤的怀疑。我们强调了中毒性表皮坏死松解症和烧伤之间的区别特征及其影响。
