Ahmad Siti Aisyah, Abdul Wahat Nor Haniza, Zakaria Mohd Normani, Wiener-Vacher Sylvette R, Abdullah Nurul Ain
Audiology Program, Faculty of Health Sciences, Universiti Kebangsaan Malaysia, 50300, Kuala Lumpur, Malaysia.
Audiology Program, Faculty of Health Sciences, Universiti Kebangsaan Malaysia, 50300, Kuala Lumpur, Malaysia.
Int J Pediatr Otorhinolaryngol. 2020 Aug;135:110132. doi: 10.1016/j.ijporl.2020.110132. Epub 2020 May 23.
Vestibular assessments in children are essential for the early identification of vestibular and balance dysfunctions. Vestibular evoked myogenic potentials, cervical (cVEMPs) and ocular (oVEMPs) have been reported to be feasible and effective when assessing otolith function in children. The main aim of the study was to obtain normative data for cVEMPs and oVEMPs from preschool and primary school-aged Malaysian children.
A group of 33 healthy children, aged from 5 years 9 months-12 years 4 months (mean ± SD = 8.83 ± 1.92 years), was recruited. Their otolith saccular function was assessed using 750 Hz tone burst for cVEMPs (with ER3A insert phone), while their utricular function was assessed using Brüel & Kjaer Mini-shaker Type 4810 (Naerum, Denmark) for oVEMPs.
For cVEMPs, the mean value of P13 latency, N23 latency, P13-N23 interamplitude and asymmetry ratio were 12.62 ± 1.38 ms, 19.85 ± 1.95 ms, 92.47 ± 50.35 μV and 14.03 ± 9.75%, respectively. For oVEMPs, the mean value of N10 latency, P15 latency, N10-P15 interamplitude and asymmetry ratio were 9.23 ± 1.07 ms, 14.41 ± 1.04 ms, 10.32 ± 5.65 μV and 15.84 ± 11.49%, respectively. Two-way ANOVA analysis found that ear laterality and gender had no significant effect on all cVEMPs and oVEMPs parameters. No significant correlation was found between age and all VEMPs parameters.
The normative data for cVEMPs and oVEMPs obtained in this study can be used as a guide by health professionals to assess saccular and utricular functions among children age from 5 to 12 years of age.
儿童前庭评估对于早期识别前庭和平衡功能障碍至关重要。据报道，前庭诱发肌源性电位，包括颈肌（cVEMPs）和眼肌（oVEMPs），在评估儿童耳石功能时是可行且有效的。本研究的主要目的是获取马来西亚学龄前和小学年龄段儿童的cVEMPs和oVEMPs的标准数据。
招募了一组33名健康儿童，年龄在5岁9个月至12岁4个月之间（平均±标准差=8.83±1.92岁）。使用750Hz短纯音（带ER3A插入式耳机）评估他们耳石球囊功能的cVEMPs，同时使用丹麦Brüel & Kjaer 4810型小型振动器评估他们椭圆囊功能的oVEMPs。
对于cVEMPs，P13潜伏期、N23潜伏期、P13 - N23波幅和不对称率的平均值分别为12.62±1.38毫秒、19.85±1.95毫秒、92.47±50.35微伏和14.03±9.75%。对于oVEMPs，N10潜伏期、P15潜伏期、N10 - P15波幅和不对称率的平均值分别为9.23±1.07毫秒、14.41±1.04毫秒、10.32±5.65微伏和15.84±11.49%。双向方差分析发现，耳侧别和性别对所有cVEMPs和oVEMPs参数均无显著影响。年龄与所有VEMPs参数之间未发现显著相关性。
本研究获得的cVEMPs和oVEMPs的标准数据可供健康专业人员用于评估5至12岁儿童的球囊和椭圆囊功能。
