感染 SARS-CoV-2 后出现 Miller-Fisher 综合征。
Miller-Fisher syndrome after SARS-CoV-2 infection.
机构信息
Neurology Department, Regional University Hospital of Málaga, Málaga, Spain.
Neurophysiology Department, Regional University Hospital of Málaga, Málaga, Spain.
出版信息
Eur J Neurol. 2020 Sep;27(9):1759-1761. doi: 10.1111/ene.14383.
Abstract
INTRODUCTION
On March 11th, 2020, the WHO declared the SARS-Cov-2 pandemic. Syndromes have been detected in relation to COVID-19 such as encephalitis, acute necrotizing hemorrhagic encephalopathy and cerebrovascular complications. There are also cases of peripheral nervous system involvement.
METHODS
Our case would be the 3rd patient with MFS associated with COVID-19 as far as we know.
RESULTS
We present a 51 years old female diagnosed with MFS two weeks after COVID-19. RTPCR to SARS-CoV-2 was negative but IgG was positive.
CONCLUSION
Most of the cases were mild or moderate with typical signs and symptoms. All were treated with IV immunoglobulin with good response in most cases. Despite the short evolution time of the cases surviving the current pandemic, the description of cases of post-infectious neurological syndromes suggests that this is probably not an infrequent complication in the subacute stage of Covid-19 disease.
摘要
简介
2020 年 3 月 11 日，世界卫生组织宣布 SARS-CoV-2 大流行。与 COVID-19 相关的综合征已被检测到，如脑炎、急性坏死性出血性脑炎和脑血管并发症。也有周围神经系统受累的病例。
方法
据我们所知，这是我们所知的第 3 例与 COVID-19 相关的 MFS 患者。
结果
我们报告了一例 51 岁女性，在 COVID-19 后两周被诊断为 MFS。SARS-CoV-2 的 RT-PCR 为阴性，但 IgG 为阳性。
结论
大多数病例为轻度或中度，有典型的体征和症状。所有患者均接受 IV 免疫球蛋白治疗，大多数患者反应良好。尽管目前大流行中存活的病例的演变时间较短，但感染后神经系统综合征的描述表明，这可能不是 COVID-19 疾病亚急性期的常见并发症。
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