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Is melatonin deficiency a unifying pathomechanism of high risk patients with COVID-19?

作者信息

Simko Fedor, Reiter Russel J

机构信息

Institute of Pathophysiology, Faculty of Medicine, Comenius University, Sasinkova 4, 811 08 Bratislava, Slovak Republic; Institute of Experimental Endocrinology, Biomedical Research Center, Slovak Academy of Sciences, Bratislava, Slovak Republic.

Department of Cell Systems and Anatomy, UT Health San Antonio, San Antonio, TX, USA.

出版信息

Life Sci. 2020 Sep 1;256:117902. doi: 10.1016/j.lfs.2020.117902. Epub 2020 Jun 3.

DOI:10.1016/j.lfs.2020.117902
PMID:32504754
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7832439/
Abstract
摘要

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本文引用的文献

1
COVID-19: Melatonin as a potential adjuvant treatment.新型冠状病毒肺炎：褪黑素作为一种潜在的辅助治疗方法。
Life Sci. 2020 Jun 1;250:117583. doi: 10.1016/j.lfs.2020.117583. Epub 2020 Mar 23.
2
Experimental models of melatonin-deficient hypertension.褪黑素缺乏性高血压的实验模型。
Front Biosci (Landmark Ed). 2013 Jan 1;18(2):616-25. doi: 10.2741/4125.
3
Melatonin in aging and disease -multiple consequences of reduced secretion, options and limits of treatment.褪黑素与衰老和疾病——分泌减少的多种后果、治疗的选择和限制。
Aging Dis. 2012 Apr;3(2):194-225. Epub 2011 Feb 10.
4
Decreased level of melatonin in serum predicts left ventricular remodelling after acute myocardial infarction.血清褪黑素水平降低可预测急性心肌梗死后左心室重构。
J Pineal Res. 2012 Oct;53(3):319-23. doi: 10.1111/j.1600-079X.2012.01001.x. Epub 2012 Apr 27.
5
Melatonin levels decrease in type 2 diabetic patients with cardiac autonomic neuropathy.2型糖尿病合并心脏自主神经病变患者的褪黑素水平降低。
J Pineal Res. 2005 Aug;39(1):43-9. doi: 10.1111/j.1600-079X.2005.00213.x.
6
Impaired nocturnal melatonin secretion in non-dipper hypertensive patients.非勺型高血压患者夜间褪黑素分泌受损。
Blood Press. 2003;12(1):19-24.