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基于音乐的干预措施改善纤维肌痛综合征:一项荟萃分析。

Music-based interventions to improve fibromyalgia syndrome: A meta-analysis.

机构信息

The Fourth Affiliated Hospital of Chengdu University of Traditional Chinese Medicine, Chongqing 400021, China; Department of Rheumatology, Chongqing Hospital of Traditional Chinese Medicine, Chongqing 400021, China.

Department of Rheumatology, Chongqing Hospital of Traditional Chinese Medicine, Chongqing 400021, China; Graduate School, Hunan University of Traditional Chinese Medicine, Changsha 410007, China.

出版信息

Explore (NY). 2020 Nov-Dec;16(6):357-362. doi: 10.1016/j.explore.2020.05.012. Epub 2020 May 25.

DOI:10.1016/j.explore.2020.05.012
PMID:32505520
Abstract

OBJECTIVE

We evaluated the effects of music therapy on pain, depression and quality of life in patients with fibromyalgia.

METHODS

Ten online databases were searched to identify randomized controlled trials that investigated the effects of music therapy on fibromyalgia patients, published up to 1st January 2019. The results were filtered and independently extracted. Statistical heterogeneity was assessed using the chi-square test. According to the outcome of the heterogeneity indices, either a fixed effect or a random effect model was used.

RESULTS

In total, seven randomized controlled trials were included. The Pain Visual Analog Scale, the McGill Pain Scale, the Beck Depression Scale and the Fibromyalgia Impact Questionnaire were used as outcome measures. Our evidence indicated that patient intervention with music therapy had lower scores on the Pain Visual Analog Scale (95% confidence interval [CI] -2.22 to -1.18, Z = 6.44, P < 0.00001, four studies) and Beck Depression Scale (95% CI -0.65 to -0.03, Z = 2.17, P = 0.03, two studies). No significant differences were observed on the McGill Pain Scale between the music intervention and control groups (95% CI -0.83 to -0.09, Z = 1.59, P = 0.11). A general qualitative description of the Fibromyalgia Impact Questionnaire results was given due to high heterogeneity (I = 96%, P < 0.00001).

CONCLUSIONS

The music therapy is superior to non-music therapy in the treatment of pain, depression, and improvement of quality of life in fibromyalgia patients. However, due to the low quantity and quality of the included studies, a larger number and high-quality of RCTs are needed to confirm the beneficial effects of music therapy.

摘要

目的

评估音乐疗法对纤维肌痛患者疼痛、抑郁和生活质量的影响。

方法

检索了 10 个在线数据库,以确定截至 2019 年 1 月 1 日研究音乐疗法对纤维肌痛患者影响的随机对照试验。对结果进行筛选和独立提取。使用卡方检验评估统计异质性。根据异质性指标的结果,使用固定效应或随机效应模型。

结果

共纳入 7 项随机对照试验。疼痛视觉模拟评分、麦吉尔疼痛量表、贝克抑郁量表和纤维肌痛影响问卷被用作结局测量指标。我们的证据表明,患者接受音乐疗法干预后的疼痛视觉模拟评分较低(95%置信区间 [CI] -2.22 至 -1.18,Z = 6.44,P < 0.00001,四项研究)和贝克抑郁量表评分较低(95% CI -0.65 至 -0.03,Z = 2.17,P = 0.03,两项研究)。音乐干预组和对照组在麦吉尔疼痛量表上的差异无统计学意义(95% CI -0.83 至 -0.09,Z = 1.59,P = 0.11)。由于高度异质性(I = 96%,P < 0.00001),对纤维肌痛影响问卷结果进行了一般定性描述。

结论

音乐疗法在治疗纤维肌痛患者的疼痛、抑郁和改善生活质量方面优于非音乐疗法。然而,由于纳入研究的数量和质量较低,需要更多高质量的 RCT 来证实音乐疗法的有益效果。

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