Mandour Yasser Mohammad, El Sayed Mohamed Aly, El Sayed Morgan Ashraf, Bassam Rehab, Fadl Hamada, Elrefae Ahmed
Faculty of Medicine, Department of Otorhinolaryngology, Benha University, Benha Faculty of Medicine, Egypt.
Faculty of Medicine, Department of Audio Vestibular Medicine, Mansoura University, Mansoura Faculty of Medicine, Egypt.
Int J Pediatr Otorhinolaryngol. 2020 Aug;135:110126. doi: 10.1016/j.ijporl.2020.110126. Epub 2020 May 20.
To evaluate the hearing of infants with history of neonatal hyperbilirubinemia using ABR.
A prospective randomized study carried on 100 infants whose hearing was assessed by ABR. Infants were allocated into two groups; case group which involve 60 infants with history of neonatal hyperbilirubinemia (bilirubin more than17 mg/dl and less than 30 mg/dl) and control group involve 40 healthy infants. Each group was divided into 3 groups based on their age i.e. ≤ 6 months, > 6-9 months &> 9-12 months. The evaluated variables were latency time & inter peak latency time.
The mean latencies of wave III&V of ABR were significantly higher in the case group compared with the controls (P < 0.001) while the mean latencies of wave I did not show a significant difference between the two study groups (P > 0.05). The mean inter wave latencies I-III, I-V& III-V of ABR were significantly higher in the case group compared with the controls. There was a negative correlation between age and the studied variables.
Hyperbilirubinemia have an adverse effect on neonatal hearing which was reflected by ABR parameters of this study.
采用听性脑干反应（ABR）评估有新生儿高胆红素血症病史婴儿的听力。
对100名通过ABR评估听力的婴儿进行一项前瞻性随机研究。将婴儿分为两组；病例组包括60名有新生儿高胆红素血症病史（胆红素大于17mg/dl且小于30mg/dl）的婴儿，对照组包括40名健康婴儿。根据年龄将每组再分为3组，即≤6个月、＞6 - 9个月和＞9 - 12个月。评估变量为潜伏期和峰间潜伏期。
病例组ABR波III和波V的平均潜伏期显著高于对照组（P＜0.001），而波I的平均潜伏期在两个研究组之间未显示出显著差异（P＞0.05）。病例组ABR的平均波间潜伏期I - III、I - V和III - V显著高于对照组。年龄与研究变量之间存在负相关。
高胆红素血症对新生儿听力有不良影响，本研究的ABR参数反映了这一点。
