Shang You, Pan Chun, Yang Xianghong, Zhong Ming, Shang Xiuling, Wu Zhixiong, Yu Zhui, Zhang Wei, Zhong Qiang, Zheng Xia, Sang Ling, Jiang Li, Zhang Jiancheng, Xiong Wei, Liu Jiao, Chen Dechang
Department of Critical Care Medicine, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Department of Critical Care Medicine, Zhongda Hospital, School of Medicine, Southeast University, Nanjing, China.
Ann Intensive Care. 2020 Jun 6;10(1):73. doi: 10.1186/s13613-020-00689-1.
The ongoing coronavirus disease 2019 (COVID-2019) pandemic has swept all over the world, posing a great pressure on critical care resources due to large number of patients needing critical care. Statements from front-line experts in the field of intensive care are urgently needed.
Sixteen front-line experts in China fighting against the COVID-19 epidemic in Wuhan were organized to develop an expert statement after 5 rounds of expert seminars and discussions to provide trustworthy recommendation on the management of critically ill COVID-19 patients. Each expert was assigned tasks within their field of expertise to provide draft statements and rationale. Parts of the expert statement are based on epidemiological and clinical evidence, without available scientific evidences.
A comprehensive document with 46 statements are presented, including protection of medical personnel, etiological treatment, diagnosis and treatment of tissue and organ functional impairment, psychological interventions, immunity therapy, nutritional support, and transportation of critically ill COVID-19 patients. Among them, 5 recommendations were strong (Grade 1), 21 were weak (Grade 2), and 20 were experts' opinions. A strong agreement from voting participants was obtained for all recommendations.
There are still no targeted therapies for COVID-19 patients. Dynamic monitoring and supportive treatment for the restoration of tissue vascularization and organ function are particularly important.
持续的2019冠状病毒病（COVID - 19）大流行已席卷全球，由于大量患者需要重症监护，给重症监护资源带来了巨大压力。迫切需要重症监护领域一线专家的声明。
组织了16名在中国武汉抗击COVID - 19疫情的一线专家，经过5轮专家研讨会和讨论后制定专家声明，以就重症COVID - 19患者的管理提供可靠建议。每位专家在其专业领域内被分配任务以提供声明草案和理由。专家声明的部分内容基于流行病学和临床证据，缺乏可用的科学证据。
呈现了一份包含46条声明的综合文件，内容包括医务人员防护、病因治疗、组织和器官功能损害的诊治、心理干预、免疫治疗、营养支持以及重症COVID - 19患者的转运。其中，5条建议为强烈推荐（1级），21条为弱推荐（2级），20条为专家意见。所有建议均获得投票参与者的强烈认可。
对于COVID - 19患者仍没有针对性的治疗方法。动态监测以及支持组织血管化和器官功能恢复的治疗尤为重要。
